Detalles de la búsqueda
1.
International Union of Basic and Clinical Pharmacology CXIII: Nuclear Receptor Superfamily-Update 2023.
Pharmacol Rev
; 75(6): 1233-1318, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37586884
2.
A Synthetic ERR Agonist Alleviates Metabolic Syndrome.
J Pharmacol Exp Ther
; 388(2): 232-240, 2024 01 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-37739806
3.
Estrogen-Related Receptor Agonism Reverses Mitochondrial Dysfunction and Inflammation in the Aging Kidney.
Am J Pathol
; 193(12): 1969-1987, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37717940
4.
Tailoring FXR Modulators for Intestinal Specificity: Recent Progress and Insights.
Molecules
; 29(9)2024 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38731514
5.
Mitochondrial pyruvate carrier inhibitors improve metabolic parameters in diet-induced obese mice.
J Biol Chem
; 298(2): 101554, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34973337
6.
Synthesis of 3-Aminoquinazolinones via a SnCl2-Mediated ANRORC-like Reductive Rearrangement of 1,3,4-Oxadiazoles.
J Org Chem
; 88(24): 17062-17068, 2023 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-38016045
7.
Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.
J Enzyme Inhib Med Chem
; 38(1): 2201407, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37078173
8.
Synthesis and structure activity relationship of the first class of LXR inverse agonists.
Bioorg Chem
; 119: 105540, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34902646
9.
Structure-based design and synthesis of conformationally constrained derivatives of methyl-piperidinopyrazole (MPP) with estrogen receptor (ER) antagonist activity.
Bioorg Chem
; 119: 105554, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34923243
10.
Ligand-based design, synthesis, computational insights, and in vitro studies of novel N-(5-Nitrothiazol-2-yl)-carboxamido derivatives as potent inhibitors of SARS-CoV-2 main protease.
J Enzyme Inhib Med Chem
; 37(1): 2112-2132, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35912578
11.
Potent antiplasmodial alkaloids from the rhizobacterium Pantoea agglomerans as hemozoin modulators.
Bioorg Chem
; 115: 105215, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34358799
12.
Design, synthesis, and pharmacological evaluation of novel and selective COX-2 inhibitors based on bumetanide scaffold.
Bioorg Chem
; 100: 103878, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32361486
13.
Modulation of estrogen-related receptors subtype selectivity: Conversion of an ERRß/γ selective agonist to ERRα/ß/γ pan agonists.
Bioorg Chem
; 102: 104079, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32683181
14.
Design and synthesis of novel pyrazolo[3,4-d]pyrimidin-4-one bearing quinoline scaffold as potent dual PDE5 inhibitors and apoptotic inducers for cancer therapy.
Bioorg Chem
; 105: 104352, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33080494
15.
Development of novel liverâ¯Xâ¯receptor modulators based on a 1,2,4-triazole scaffold.
Bioorg Med Chem Lett
; 29(3): 449-453, 2019 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30587446
16.
Baclofen impurities: Facile synthesis and novel environmentally benign chromatographic method for their simultaneous determination in baclofen.
Biomed Chromatogr
; 33(9): e4579, 2019 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-31077429
17.
2,5-Diketopiperazines (DKPs): Promising Scaffolds for Anticancer Agents.
Curr Pharm Des
; 30(8): 597-623, 2024.
Artículo
en Inglés
| MEDLINE | ID: mdl-38343054
18.
REV-ERB activation as a novel pharmacological approach for treating inflammatory pain.
Front Pharmacol
; 14: 1171931, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37153791
19.
4-(5-Amino-pyrazol-1-yl)benzenesulfonamide derivatives as novel multi-target anti-inflammatory agents endowed with inhibitory activity against COX-2, 5-LOX and carbonic anhydrase: Design, synthesis, and biological assessments.
Eur J Med Chem
; 250: 115180, 2023 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36796297
20.
Synthetic ERRα/ß/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity.
ACS Chem Biol
; 18(4): 756-771, 2023 04 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36988910