Detalles de la búsqueda
1.
Design, synthesis, and anticancer evaluation of N-sulfonylpiperidines as potential VEGFR-2 inhibitors, apoptotic inducers.
Bioorg Chem
; 145: 107157, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38340473
2.
New apoptotic anti-triple-negative breast cancer theobromine derivative inhibiting EGFRWT and EGFRT790M: in silico and in vitro evaluation.
Mol Divers
; 2023 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37162644
3.
Novel promising benzoxazole/benzothiazole-derived immunomodulatory agents: Design, synthesis, anticancer evaluation, and in silico ADMET analysis.
Arch Pharm (Weinheim)
; 356(9): e2300097, 2023 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-37379240
4.
Computer-assisted drug discovery (CADD) of an anti-cancer derivative of the theobromine alkaloid inhibiting VEGFR-2.
Saudi Pharm J
; 31(12): 101852, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38028225
5.
Design, synthesis and molecular docking of new fused 1H-pyrroles, pyrrolo[3,2-d]pyrimidines and pyrrolo[3,2-e][1, 4]diazepine derivatives as potent EGFR/CDK2 inhibitors.
J Enzyme Inhib Med Chem
; 37(1): 1884-1902, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35801486
6.
Design and synthesis of thiazolidine-2,4-diones hybrids with 1,2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: in-vitro anticancer evaluation and in-silico studies.
J Enzyme Inhib Med Chem
; 37(1): 1903-1917, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35801403
7.
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.
J Enzyme Inhib Med Chem
; 37(1): 397-410, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34961427
8.
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation.
J Enzyme Inhib Med Chem
; 37(1): 2063-2077, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35875937
9.
A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease.
Int J Mol Sci
; 23(15)2022 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955547
10.
Multi-Step In Silico Discovery of Natural Drugs against COVID-19 Targeting Main Protease.
Int J Mol Sci
; 23(13)2022 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-35805916
11.
New Anticancer Theobromine Derivative Targeting EGFRWT and EGFRT790M: Design, Semi-Synthesis, In Silico, and In Vitro Anticancer Studies.
Molecules
; 27(18)2022 Sep 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36144596
12.
Screening a Panel of Topical Ophthalmic Medications against MMP-2 and MMP-9 to Investigate Their Potential in Keratoconus Management.
Molecules
; 27(11)2022 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35684529
13.
Design, Synthesis, Docking, DFT, MD Simulation Studies of a New Nicotinamide-Based Derivative: In Vitro Anticancer and VEGFR-2 Inhibitory Effects.
Molecules
; 27(14)2022 Jul 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35889478
14.
(E)-N-(3-(1-(2-(4-(2,2,2-Trifluoroacetamido)benzoyl)hydrazono)ethyl)phenyl)nicotinamide: A Novel Pyridine Derivative for Inhibiting Vascular Endothelial Growth Factor Receptor-2: Synthesis, Computational, and Anticancer Studies.
Molecules
; 27(22)2022 Nov 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36431818
15.
Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation.
Molecules
; 27(15)2022 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35956997
16.
Discovery of Some Heterocyclic Molecules as Bone Morphogenetic Protein 2 (BMP-2)-Inducible Kinase Inhibitors: Virtual Screening, ADME Properties, and Molecular Docking Simulations.
Molecules
; 27(17)2022 Aug 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36080338
17.
Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.
Bioorg Chem
; 112: 104947, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33964580
18.
New quinoxaline derivatives as VEGFR-2 inhibitors with anticancer and apoptotic activity: Design, molecular modeling, and synthesis.
Bioorg Chem
; 110: 104807, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33721808
19.
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers.
J Enzyme Inhib Med Chem
; 36(1): 1093-1114, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34056992
20.
Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers.
J Enzyme Inhib Med Chem
; 36(1): 1760-1782, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34340610