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1.
The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats.
Int J Mol Sci
; 24(17)2023 Aug 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-37686032
2.
Methodological considerations for measuring biofluid-based microRNA biomarkers.
Crit Rev Toxicol
; 51(3): 264-282, 2021 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34038674
3.
A cross-industry survey on photosafety evaluation of pharmaceuticals after implementation of ICH S10.
Regul Toxicol Pharmacol
; 125: 105017, 2021 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-34311056
4.
A cross-sector call to improve carcinogenicity risk assessment through use of genomic methodologies.
Regul Toxicol Pharmacol
; 110: 104526, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-31726190
5.
Development and validation of a high-throughput transcriptomic biomarker to address 21st century genetic toxicology needs.
Proc Natl Acad Sci U S A
; 114(51): E10881-E10889, 2017 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29203651
6.
Energy metabolism modulation by biguanides in comparison with rotenone in rat liver and heart.
Arch Toxicol
; 93(9): 2603-2615, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31324951
7.
Prediction of human drug-induced liver injury (DILI) in relation to oral doses and blood concentrations.
Arch Toxicol
; 93(6): 1609-1637, 2019 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-31250071
8.
Two approaches for estimating the lower limit of quantitation (LLOQ) of microRNA levels assayed as exploratory biomarkers by RT-qPCR.
BMC Biotechnol
; 18(1): 6, 2018 02 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29391006
9.
Toxicogenomics directory of rat hepatotoxicants in vivo and in cultivated hepatocytes.
Arch Toxicol
; 92(12): 3517-3533, 2018 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-30511339
10.
Time-matched analysis of DNA adduct formation and early gene expression as predictive tool for renal carcinogenesis in methylazoxymethanol acetate treated Eker rats.
Arch Toxicol
; 91(10): 3427-3438, 2017 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-28349193
11.
Pharmacokinetics explain in vivo/in vitro discrepancies of carcinogen-induced gene expression alterations in rat liver and cultivated hepatocytes.
Arch Toxicol
; 87(2): 337-45, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23274394
12.
Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data.
Arch Toxicol
; 86(11): 1703-15, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23052194
13.
Comparison of hepatocarcinogen-induced gene expression profiles in conventional primary rat hepatocytes with in vivo rat liver.
Arch Toxicol
; 86(9): 1399-411, 2012 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-22484513
14.
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model.
Arch Toxicol
; 86(4): 571-89, 2012 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-22124623
15.
Urinary miRNA Profiles in Chronic Kidney Injury-Benefits of Extracellular Vesicle Enrichment and miRNAs as Potential Biomarkers for Renal Fibrosis, Glomerular Injury, and Endothelial Dysfunction.
Toxicol Sci
; 187(1): 35-50, 2022 04 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-35244176
16.
Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip® assay in TK6 cells.
Front Toxicol
; 4: 991590, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-36211197
17.
A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.
Toxicol Sci
; 188(1): 4-16, 2022 06 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-35404422
18.
EU framework 6 project: predictive toxicology (PredTox)--overview and outcome.
Toxicol Appl Pharmacol
; 252(2): 73-84, 2011 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20955723
19.
The enhanced value of combining conventional and "omics" analyses in early assessment of drug-induced hepatobiliary injury.
Toxicol Appl Pharmacol
; 252(2): 97-111, 2011 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-20888850
20.
Urinary miRNA Biomarkers of Drug-Induced Kidney Injury and Their Site Specificity Within the Nephron.
Toxicol Sci
; 180(1): 1-16, 2021 02 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-33367795