Detalles de la búsqueda
1.
Refine and Strengthen SAR-Based Read-Across by Considering Bioactivation and Modes of Action.
Chem Res Toxicol
; 36(9): 1532-1548, 2023 09 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37594911
2.
Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data.
Arch Toxicol
; 97(1): 155-164, 2023 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-36149470
3.
Impact of chemical structure on the in vitro hydrolysis of fatty esters of 2-ethylhexanoic acid or 2-ethylhexanol and extrapolation to the in vivo situation.
Regul Toxicol Pharmacol
; 137: 105315, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36494001
4.
Towards best use and regulatory acceptance of generic physiologically based kinetic (PBK) models for in vitro-to-in vivo extrapolation (IVIVE) in chemical risk assessment.
Arch Toxicol
; 96(12): 3407-3419, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36063173
5.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Regul Toxicol Pharmacol
; 132: 105161, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-35508214
6.
Application of structural and functional pharmacokinetic analogs for physiologically based pharmacokinetic model development and evaluation.
Regul Toxicol Pharmacol
; 114: 104667, 2020 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-32387187
7.
Use of human liver and EpiSkin™ S9 subcellular fractions as a screening assays to compare the in vitro hepatic and dermal metabolism of 47 cosmetics-relevant chemicals.
J Appl Toxicol
; 40(3): 416-433, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31912921
8.
Comparison of the metabolism of 10 cosmetics-relevant chemicals in EpiSkin™ S9 subcellular fractions and in vitro human skin explants.
J Appl Toxicol
; 40(2): 313-326, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31701564
9.
Measurement of the penetration of 56 cosmetic relevant chemicals into and through human skin using a standardized protocol.
J Appl Toxicol
; 40(3): 403-415, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31867769
10.
Challenges in working towards an internal threshold of toxicological concern (iTTC) for use in the safety assessment of cosmetics: Discussions from the Cosmetics Europe iTTC Working Group workshop.
Regul Toxicol Pharmacol
; 103: 63-72, 2019 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-30653989
11.
Use of a Simple in vitro Test to Assess Loss of Chemical due to Volatility during an in vitro Human Skin Absorption Study.
Skin Pharmacol Physiol
; 32(3): 117-124, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30889606
12.
Correction to: Practical application of the interim internal threshold of toxicological concern (iTTC): a case study based on clinical data.
Arch Toxicol
; 97(1): 311, 2023 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-36437304
13.
Structural and functional pharmacokinetic analogs for physiologically based pharmacokinetic (PBPK) model evaluation.
Regul Toxicol Pharmacol
; 99: 61-77, 2018 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-30201539
14.
Comparison of the Skin Penetration of 3 Metabolically Stable Chemicals Using Fresh and Frozen Human Skin.
Skin Pharmacol Physiol
; 30(5): 234-245, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28746940
15.
Comparison between endocrine activity assessed using ToxCast/Tox21 database and human plasma concentration of sunscreen active ingredients/UV filters.
Toxicol Sci
; 196(1): 25-37, 2023 10 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37561120
16.
Structure-activity relationship read-across and transcriptomics for branched carboxylic acids.
Toxicol Sci
; 191(2): 343-356, 2023 02 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36583546
17.
Human hepatic cytochrome P450-specific metabolism of the organophosphorus pesticides methyl parathion and diazinon.
Drug Metab Dispos
; 40(1): 1-5, 2012 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-21969518
18.
PON1 status does not influence cholinesterase activity in Egyptian agricultural workers exposed to chlorpyrifos.
Toxicol Appl Pharmacol
; 265(3): 308-15, 2012 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22975224
19.
Allele and genotype frequencies of CYP2B6 and CYP2C19 polymorphisms in Egyptian agricultural workers.
J Toxicol Environ Health A
; 75(4): 232-41, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22352331
20.
Metabolism and plasma protein binding of 16 straight- and branched-chain parabens in in vitro liver and skin models.
Toxicol In Vitro
; 72: 105051, 2021 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-33188879