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1.
Indenoisoquinoline Topoisomerase Inhibitors Strongly Bind and Stabilize the MYC Promoter G-Quadruplex and Downregulate MYC.
J Am Chem Soc
; 141(28): 11059-11070, 2019 07 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-31283877
2.
Design, synthesis and molecular modeling study of certain 4-Methylbenzenesulfonamides with CDK2 inhibitory activity as anticancer and radio-sensitizing agents.
Bioorg Chem
; 80: 276-287, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29966874
3.
Ligand-free, palladacycle-facilitated Suzuki coupling of hindered 2-arylbenzothiazole derivatives yields potent and selective COX-2 inhibitors.
Org Biomol Chem
; 16(1): 108-118, 2017 Dec 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29199735
4.
Discovery of 5-Azaquinoxaline Derivatives as Potent and Orally Bioavailable Allosteric SHP2 Inhibitors.
ACS Med Chem Lett
; 14(12): 1673-1681, 2023 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38116446
5.
Synthesis of Benzo[1,6]naphthyridinones Using the Catellani Reaction.
Org Lett
; 20(17): 5228-5232, 2018 09 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30102543
6.
Application of Sequential Palladium Catalysis for the Discovery of Janus Kinase Inhibitors in the Benzo[ c]pyrrolo[2,3- h][1,6]naphthyridin-5-one (BPN) Series.
J Med Chem
; 61(23): 10440-10462, 2018 12 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-30460842
7.
Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors.
Mol Cancer Ther
; 17(8): 1694-1704, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29748210
8.
Isolation and characterization of Salmonella Enteritidis and Salmonella Typhimurium from chicken meat in Egypt.
J Infect Dev Ctries
; 11(4): 314-319, 2017 Apr 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28459222
9.
Synthesis and Biological Evaluation of the First Triple Inhibitors of Human Topoisomerase 1, Tyrosyl-DNA Phosphodiesterase 1 (Tdp1), and Tyrosyl-DNA Phosphodiesterase 2 (Tdp2).
J Med Chem
; 60(8): 3275-3288, 2017 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-28418653
10.
Design and Synthesis of Chlorinated and Fluorinated 7-Azaindenoisoquinolines as Potent Cytotoxic Anticancer Agents That Inhibit Topoisomerase I.
J Med Chem
; 60(13): 5364-5376, 2017 07 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-28657311
11.
Synthesis of indolo[4,3-bc]phenanthridine-6,11(2H,12H)-diones using the Schiff base-homophthalic anhydride cyclization reaction.
Synth Commun
; 46(23): 1902-1908, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-29056779
12.
Design, Synthesis, and Biological Evaluation of Potential Prodrugs Related to the Experimental Anticancer Agent Indotecan (LMP400).
J Med Chem
; 59(10): 4890-9, 2016 05 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-27097152
13.
Structure-based design and synthesis of novel pseudosaccharine derivatives as antiproliferative agents and kinase inhibitors.
Eur J Med Chem
; 61: 122-31, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23063746
14.
Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors.
PLoS One
; 7(11): e49284, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-23185312
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