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1.
Validation of cell-based OATP1B1 assays to assess drug transport and the potential for drug-drug interaction to support regulatory submissions.
Xenobiotica
; 40(1): 24-37, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19919292
2.
Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions.
Xenobiotica
; 38(7-8): 1140-64, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18668443
3.
Effects of Fostamatinib on the Pharmacokinetics of Oral Contraceptive, Warfarin, and the Statins Rosuvastatin and Simvastatin: Results From Phase I Clinical Studies.
Drugs R D
; 16(1): 93-107, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26748647
4.
Obstacles to the prediction of estrogenicity from chemical structure: assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor.
Biochem Pharmacol
; 60(10): 1519-30, 2000 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-11020455
5.
Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.
Clin Pharmacol Ther
; 94(1): 126-41, 2013 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-23588320
6.
Understanding the critical disposition pathways of statins to assess drug-drug interaction risk during drug development: it's not just about OATP1B1.
Clin Pharmacol Ther
; 92(5): 584-98, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23047648
7.
Comparison of the modulatory effects of human and rat liver microsomal metabolism on the estrogenicity of bisphenol A: implications for extrapolation to humans.
J Pharmacol Exp Ther
; 297(1): 103-13, 2001 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-11259533
8.
Assessment of the effects of metabolism on the estrogenic activity of xenoestrogens: a two-stage approach coupling human liver microsomes and a yeast estrogenicity assay.
J Pharmacol Exp Ther
; 296(2): 329-37, 2001 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-11160614
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