Detalles de la búsqueda
1.
Design, synthesis and molecular docking of new [1,2,4] triazolo[4,3-a]quinoxaline derivatives as anticancer agents targeting VEGFR-2 kinase.
Mol Divers
; 26(4): 1915-1932, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-34460053
2.
Design, synthesis, molecular modeling and biological evaluation of novel Benzoxazole-Benzamide conjugates via a 2-Thioacetamido linker as potential anti-proliferative agents, VEGFR-2 inhibitors and apoptotic inducers.
J Enzyme Inhib Med Chem
; 37(1): 1587-1599, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35637622
3.
Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.
J Enzyme Inhib Med Chem
; 37(1): 1556-1567, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35635148
4.
New benzoxazole derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative evaluation, flowcytometric analysis, and in silico studies.
J Enzyme Inhib Med Chem
; 37(1): 397-410, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34961427
5.
Anti-cancer and immunomodulatory evaluation of new nicotinamide derivatives as potential VEGFR-2 inhibitors and apoptosis inducers: in vitro and in silico studies.
J Enzyme Inhib Med Chem
; 37(1): 2206-2222, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35980113
6.
Benzoxazole derivatives as new VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, in silico studies, and antiproliferative evaluation.
J Enzyme Inhib Med Chem
; 37(1): 2063-2077, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35875937
7.
New [1,2,4]triazolo[4,3-c]quinazoline derivatives as vascular endothelial growth factor receptor-2 inhibitors and apoptosis inducers: Design, synthesis, docking, and antiproliferative evaluation.
Arch Pharm (Weinheim)
; 355(10): e2200133, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-35822666
8.
Targeting VEGFR-2 by new quinoxaline derivatives: Design, synthesis, antiproliferative assay, apoptosis induction, and in silico studies.
Arch Pharm (Weinheim)
; 355(2): e2100359, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-34862634
9.
A Multistage In Silico Study of Natural Potential Inhibitors Targeting SARS-CoV-2 Main Protease.
Int J Mol Sci
; 23(15)2022 Jul 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35955547
10.
Design, Synthesis, In Silico and In Vitro Studies of New Immunomodulatory Anticancer Nicotinamide Derivatives Targeting VEGFR-2.
Molecules
; 27(13)2022 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-35807326
11.
Modified Benzoxazole-Based VEGFR-2 Inhibitors and Apoptosis Inducers: Design, Synthesis, and Anti-Proliferative Evaluation.
Molecules
; 27(15)2022 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35956997
12.
Discovery of thieno[2,3-d]pyrimidine-based derivatives as potent VEGFR-2 kinase inhibitors and anti-cancer agents.
Bioorg Chem
; 112: 104947, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33964580
13.
Discovery of new VEGFR-2 inhibitors based on bis([1, 2, 4]triazolo)[4,3-a:3',4'-c]quinoxaline derivatives as anticancer agents and apoptosis inducers.
J Enzyme Inhib Med Chem
; 36(1): 1093-1114, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34056992
14.
Design, synthesis, docking, ADMET studies, and anticancer evaluation of new 3-methylquinoxaline derivatives as VEGFR-2 inhibitors and apoptosis inducers.
J Enzyme Inhib Med Chem
; 36(1): 1760-1782, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34340610
15.
Design, synthesis, molecular docking and anti-proliferative evaluations of [1,2,4]triazolo[4,3-a]quinoxaline derivatives as DNA intercalators and Topoisomerase II inhibitors.
Bioorg Chem
; 105: 104399, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33113414
16.
Discovery of new thiazolidine-2,4-dione derivatives as potential VEGFR-2 inhibitors: In vitro and in silico studies.
Heliyon
; 10(2): e24005, 2024 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-38298627
17.
New thiazolidine-2,4-diones as potential anticancer agents and apoptotic inducers targeting VEGFR-2 kinase: Design, synthesis, in silico and in vitro studies.
Biochim Biophys Acta Gen Subj
; 1868(6): 130599, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38521471
18.
New theobromine derivatives inhibiting VEGFR-2: design, synthesis, antiproliferative, docking and molecular dynamics simulations.
Future Med Chem
; 15(14): 1233-1250, 2023 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37466069
19.
New thiazolidine-2,4-diones as effective anti-proliferative and anti-VEGFR-2 agents: Design, synthesis, in vitro, docking, MD simulations, DFT, ADMET, and toxicity studies.
Comput Biol Chem
; 107: 107958, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37714080
20.
Semi-synthesized anticancer theobromine derivatives targeting VEGFR-2: in silico and in vitro evaluations.
J Biomol Struct Dyn
; : 1-20, 2023 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37261471