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1.

HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis.

Emmons, Michael F; Bennett, Richard L; Riva, Alberto; Gupta, Kanchan; Carvalho, Larissa Anastasio Da Costa; Zhang, Chao; Macaulay, Robert; Dupéré-Richér, Daphne; Fang, Bin; Seto, Edward; Koomen, John M; Li, Jiannong; Chen, Y Ann; Forsyth, Peter A; Licht, Jonathan D; Smalley, Keiran S M.

Nat Commun ; 14(1): 7759, 2023 Nov 29.

Artículo en Inglés | MEDLINE | ID: mdl-38030596

2.

Ironing-Out the Details: New Strategies for Combining Ferroptosis Inhibitors with Immunotherapy in Melanoma.

Emmons, Michael F; Smalley, Keiran S M.

J Invest Dermatol ; 142(1): 18-20, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34565560

3.

HDAC11 activity contributes to MEK inhibitor escape in uveal melanoma.

Sriramareddy, Sathya Neelature; Faião-Flores, Fernanda; Emmons, Michael F; Saha, Biswarup; Chellappan, Srikumar; Wyatt, Clayton; Smalley, Inna; Licht, Jonathan D; Durante, Michael A; Harbour, J William; Smalley, Keiran S M.

Cancer Gene Ther ; 29(12): 1840-1846, 2022 12.

Artículo en Inglés | MEDLINE | ID: mdl-35332245

4.

Noncanonical EphA2 Signaling Is a Driver of Tumor-Endothelial Cell Interactions and Metastatic Dissemination in BRAF InhibitorâResistant Melanoma.

Zhang, Chao; Smalley, Inna; Emmons, Michael F; Sharma, Ritin; Izumi, Victoria; Messina, Jane; Koomen, John M; Pasquale, Elena B; Forsyth, Peter A; Smalley, Keiran S M.

J Invest Dermatol ; 141(4): 840-851.e4, 2021 04.

Artículo en Inglés | MEDLINE | ID: mdl-32890629

5.

Decitabine limits escape from MEK inhibition in uveal melanoma.

Gonçalves, Jessica; Emmons, Michael F; Faião-Flores, Fernanda; Aplin, Andrew E; Harbour, J William; Licht, Jonathan D; Wink, Márcia R; Smalley, Keiran S M.

Pigment Cell Melanoma Res ; 33(3): 507-514, 2020 05.

Artículo en Inglés | MEDLINE | ID: mdl-31758842

6.

Stat3 contributes to resistance toward BCR-ABL inhibitors in a bone marrow microenvironment model of drug resistance.

Bewry, Nadine N; Nair, Rajesh R; Emmons, Michael F; Boulware, David; Pinilla-Ibarz, Javier; Hazlehurst, Lori A.

Mol Cancer Ther ; 7(10): 3169-75, 2008 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-18852120

7.

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy.

Emmons, Michael F; Faião-Flores, Fernanda; Sharma, Ritin; Thapa, Ram; Messina, Jane L; Becker, Jurgen C; Schadendorf, Dirk; Seto, Edward; Sondak, Vernon K; Koomen, John M; Chen, Yian A; Lau, Eric K; Wan, Lixin; Licht, Jonathan D; Smalley, Keiran S M.

Cancer Res ; 79(11): 2947-2961, 2019 06 01.

Artículo en Inglés | MEDLINE | ID: mdl-30987999

8.

HDAC Inhibition Enhances the In Vivo Efficacy of MEK Inhibitor Therapy in Uveal Melanoma.

Faião-Flores, Fernanda; Emmons, Michael F; Durante, Michael A; Kinose, Fumi; Saha, Biswarup; Fang, Bin; Koomen, John M; Chellappan, Srikumar P; Maria-Engler, Silvya Stuchi; Rix, Uwe; Licht, Jonathan D; Harbour, J William; Smalley, Keiran S M.

Clin Cancer Res ; 25(18): 5686-5701, 2019 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-31227503

9.

Cell adhesion to fibronectin (CAM-DR) influences acquired mitoxantrone resistance in U937 cells.

Hazlehurst, Lori A; Argilagos, Raul F; Emmons, Michael; Boulware, David; Beam, Craig A; Sullivan, Dan M; Dalton, William S.

Cancer Res ; 66(4): 2338-45, 2006 Feb 15.

Artículo en Inglés | MEDLINE | ID: mdl-16489039

10.

MTI-101 treatment inducing activation of Stim1 and TRPC1 expression is a determinant of response in multiple myeloma.

Emmons, Michael F; Anreddy, Nagaraju; Cuevas, Javier; Steinberger, Kayla; Yang, Shengyu; McLaughlin, Mark; Silva, Ariosto; Hazlehurst, Lori A.

Sci Rep ; 7(1): 2685, 2017 06 02.

Artículo en Inglés | MEDLINE | ID: mdl-28578393

11.

The role of phenotypic plasticity in the escape of cancer cells from targeted therapy.

Emmons, Michael F; Faião-Flores, Fernanda; Smalley, Keiran S M.

Biochem Pharmacol ; 122: 1-9, 2016 Dec 15.

Artículo en Inglés | MEDLINE | ID: mdl-27349985

12.

MTI-101 (cyclized HYD1) binds a CD44 containing complex and induces necrotic cell death in multiple myeloma.

Gebhard, Anthony W; Jain, Priyesh; Nair, Rajesh R; Emmons, Michael F; Argilagos, Raul F; Koomen, John M; McLaughlin, Mark L; Hazlehurst, Lori A.

Mol Cancer Ther ; 12(11): 2446-58, 2013 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-24048737

13.

CRM1 Inhibition Sensitizes Drug Resistant Human Myeloma Cells to Topoisomerase II and Proteasome Inhibitors both In Vitro and Ex Vivo.

Turner, Joel G; Dawson, Jana; Emmons, Michael F; Cubitt, Christopher L; Kauffman, Michael; Shacham, Sharon; Hazlehurst, Lori A; Sullivan, Daniel M.

J Cancer ; 4(8): 614-25, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24155773

14.

Emerging strategies for targeting cell adhesion in multiple myeloma.

Nair, Rajesh R; Gebhard, Anthony W; Emmons, Michael F; Hazlehurst, Lori A.

Adv Pharmacol ; 65: 143-89, 2012.

Artículo en Inglés | MEDLINE | ID: mdl-22959026

15.

Acquisition of resistance toward HYD1 correlates with a reduction in cleaved α4 integrin expression and a compromised CAM-DR phenotype.

Emmons, Michael F; Gebhard, Anthony W; Nair, Rajesh R; Baz, Rachid; McLaughlin, Mark L; Cress, Anne E; Hazlehurst, Lori A.

Mol Cancer Ther ; 10(12): 2257-66, 2011 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-21980133

16.

Human multiple myeloma cells are sensitized to topoisomerase II inhibitors by CRM1 inhibition.

Turner, Joel G; Marchion, Douglas C; Dawson, Jana L; Emmons, Michael F; Hazlehurst, Lori A; Washausen, Peter; Sullivan, Daniel M.

Cancer Res ; 69(17): 6899-905, 2009 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-19690141

17.

HYD1-induced increase in reactive oxygen species leads to autophagy and necrotic cell death in multiple myeloma cells.

Nair, Rajesh R; Emmons, Michael F; Cress, Anne E; Argilagos, Raul F; Lam, Kit; Kerr, William T; Wang, Hong-Gong; Dalton, William S; Hazlehurst, Lori A.

Mol Cancer Ther ; 8(8): 2441-51, 2009 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-19671765

18.

Comportamento assertivo: um guia de auto-expressão

Robert, E. Alberti; Emmons, Michael L.

Belo Horizonte; Interlivros; 1978. 147 p.

Monografía en Portugués | MS | ID: mis-12539

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