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1.
Model-informed precision dosing for alemtuzumab in paediatric and young adult patients undergoing allogeneic haematopoietic cell transplantation.
Br J Clin Pharmacol
; 88(1): 248-259, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34182590
2.
Optimal Teicoplanin Dosing Regimen in Neonates and Children Developed by Leveraging Real-World Clinical Information.
Ther Drug Monit
; 44(3): 404-413, 2022 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34629445
3.
Teicoplanin physiologically based pharmacokinetic modeling offers a quantitative assessment of a theoretical influence of serum albumin and renal function on its disposition.
Eur J Clin Pharmacol
; 77(8): 1157-1168, 2021 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-33527208
4.
Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients.
Br J Clin Pharmacol
; 86(5): 933-943, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31851762
5.
Busulfan Pharmacokinetics and Precision Dosing: Are Patients with Fanconi Anemia Different?
Biol Blood Marrow Transplant
; 25(12): 2416-2421, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31326610
6.
Evidence of a clinically significant drug-drug interaction between cannabidiol and tacrolimus.
Am J Transplant
; 19(10): 2944-2948, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31012522
7.
Adult and infant pharmacokinetic profiling of dihydrocodeine using physiologically based pharmacokinetic modeling.
Biopharm Drug Dispos
; 40(9): 350-357, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31691978
8.
Pretransplant Absolute Lymphocyte Counts Impact the Pharmacokinetics of Alemtuzumab.
Biol Blood Marrow Transplant
; 23(4): 635-641, 2017 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-28089878
9.
Developmental Changes in Hepatic Organic Cation Transporter OCT1 Protein Expression from Neonates to Children.
Drug Metab Dispos
; 45(1): 23-26, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27780835
10.
Developmental pharmacokinetics of sirolimus: Implications for precision dosing in neonates and infants with complicated vascular anomalies.
Pediatr Blood Cancer
; 64(8)2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28205374
11.
A Prospective Study of Alemtuzumab as a Second-Line Agent for Steroid-Refractory Acute Graft-versus-Host Disease in Pediatric and Young Adult Allogeneic Hematopoietic Stem Cell Transplantation.
Biol Blood Marrow Transplant
; 22(12): 2220-2225, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27664325
12.
Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients.
Ther Drug Monit
; 38(5): 607-13, 2016 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-27310200
13.
The impact of CYP3A5*3 polymorphism on sirolimus pharmacokinetics: insights from predictions with a physiologically-based pharmacokinetic model.
Br J Clin Pharmacol
; 80(6): 1438-46, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26256674
14.
Clinical Applications of Physiologically Based Pharmacokinetic Modeling: Perspectives on the Advantages and Challenges.
Ther Drug Monit
; 42(1): 157-158, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31725065
15.
Age-dependent changes in sirolimus metabolite formation in patients with neurofibromatosis type 1.
Ther Drug Monit
; 37(3): 395-9, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25162215
16.
Human pharmacokinetic profiling of the dipeptidyl peptidase-IV inhibitor teneligliptin using physiologically based pharmacokinetic modeling.
Biopharm Drug Dispos
; 36(3): 148-62, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25450725
17.
Quantitative prediction of CYP3A-mediated drug-drug interactions by correctly estimating fraction metabolized using human liver chimeric mice.
Br J Pharmacol
; 181(7): 1091-1106, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-37872109
18.
Development and Verification of a Japanese Pediatric Physiologically Based Pharmacokinetic Model with Emphasis on Drugs Eliminated by Cytochrome P450 or Renal Excretion.
J Clin Pharmacol
; 63(10): 1156-1168, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37496106
19.
Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes.
Xenobiotica
; 42(8): 719-30, 2012 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-22324396
20.
Cytochrome P450 enzymes in the pediatric population: Connecting knowledge on P450 expression with pediatric pharmacokinetics.
Adv Pharmacol
; 95: 365-391, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35953161