Detalles de la búsqueda
1.
New Perspectives on Drug-Induced Liver Injury Risk Assessment of Acyl Glucuronides.
Chem Res Toxicol
; 33(7): 1551-1560, 2020 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32525307
2.
Fevipiprant has a low risk of influencing co-medication pharmacokinetics: Impact on simvastatin and rosuvastatin in different SLCO1B1 genotypes.
Pulm Pharmacol Ther
; 57: 101809, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31195091
3.
Drug-induced liver injury: recent advances in diagnosis and risk assessment.
Gut
; 66(6): 1154-1164, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28341748
4.
Absorption, Distribution, Metabolism, and Excretion of the Oral Prostaglandin D2 Receptor 2 Antagonist Fevipiprant (QAW039) in Healthy Volunteers and In Vitro.
Drug Metab Dispos
; 45(7): 817-825, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28442499
5.
Novel Bruton's tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions.
Eur J Pharm Sci
; 172: 106155, 2022 May 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35247543
6.
Novel Bruton's Tyrosine Kinase inhibitor remibrutinib: Drug-drug interaction potential as a victim of CYP3A4 inhibitors based on clinical data and PBPK modeling.
Clin Transl Sci
; 15(1): 118-129, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34432364
7.
A Unidirectional 96-Well Fluidic Culture Platform for Upstream Cell Dosing with Subsequent Downstream Nonlinear and Ascending Exposure Gradients for Real-Time and Cell-Based Toxicity Screening Environments.
Appl In Vitro Toxicol
; 7(4): 175-191, 2021 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35028338
8.
Remibrutinib (LOU064): A selective potent oral BTK inhibitor with promising clinical safety and pharmacodynamics in a randomized phase I trial.
Clin Transl Sci
; 14(5): 1756-1768, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-33834628
9.
Addition of iptacopan, an oral factor B inhibitor, to eculizumab in patients with paroxysmal nocturnal haemoglobinuria and active haemolysis: an open-label, single-arm, phase 2, proof-of-concept trial.
Lancet Haematol
; 8(5): e344-e354, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33765419
10.
High-Throughput Melanin-Binding Affinity and In Silico Methods to Aid in the Prediction of Drug Exposure in Ocular Tissue.
J Pharm Sci
; 104(12): 3997-4001, 2015 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-26524700
11.
Discovery of BAF312 (Siponimod), a Potent and Selective S1P Receptor Modulator.
ACS Med Chem Lett
; 4(3): 333-7, 2013 Mar 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-24900670
12.
Urinary clusterin, cystatin C, beta2-microglobulin and total protein as markers to detect drug-induced kidney injury.
Nat Biotechnol
; 28(5): 463-9, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20458316
13.
Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers.
Drug Metab Dispos
; 35(8): 1418-28, 2007 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-17510248
Resultados
1 -
13
de 13
1
Próxima >
>>