Detalles de la búsqueda
1.
Repurposing of rabeprazole as an anti-Trypanosoma cruzi drug that targets cellular triosephosphate isomerase.
J Enzyme Inhib Med Chem
; 38(1): 2231169, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37401012
2.
Human Triosephosphate Isomerase Is a Potential Target in Cancer Due to Commonly Occurring Post-Translational Modifications.
Molecules
; 28(16)2023 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-37630415
3.
Improved yield, stability, and cleavage reaction of a novel tobacco etch virus protease mutant.
Appl Microbiol Biotechnol
; 106(4): 1475-1492, 2022 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-35092453
4.
The Giardial Arginine Deiminase Participates in Giardia-Host Immunomodulation in a Structure-Dependent Fashion via Toll-like Receptors.
Int J Mol Sci
; 23(19)2022 Sep 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36232855
5.
Giardia lamblia G6PD::6PGL Fused Protein Inhibitors Decrease Trophozoite Viability: A New Alternative against Giardiasis.
Int J Mol Sci
; 23(22)2022 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-36430836
6.
Kinetic and Molecular Docking Studies to Determine the Effect of Inhibitors on the Activity and Structure of Fused G6PD::6PGL Protein from Trichomonas vaginalis.
Molecules
; 27(4)2022 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35208965
7.
Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against Giardia lamblia and Trichomonas vaginalis.
Molecules
; 27(24)2022 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-36558035
8.
Multilevel Approach for the Treatment of Giardiasis by Targeting Arginine Deiminase.
Int J Mol Sci
; 22(17)2021 Aug 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-34502400
9.
Identification and In Silico Characterization of Novel Helicobacter pylori Glucose-6-Phosphate Dehydrogenase Inhibitors.
Molecules
; 26(16)2021 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-34443540
10.
Functional characterization and subcellular distribution of two recombinant cytosolic HSP70 isoforms from Entamoeba histolytica under normal and stress conditions.
Parasitol Res
; 119(4): 1337-1351, 2020 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-32056023
11.
Rabeprazole inhibits several functions of Entamoeba histolytica related with its virulence.
Parasitol Res
; 119(10): 3491-3502, 2020 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-32886229
12.
Differential effects on enzyme stability and kinetic parameters of mutants related to human triosephosphate isomerase deficiency.
Biochim Biophys Acta Gen Subj
; 1862(6): 1401-1409, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29571745
13.
Proton pump inhibitors drastically modify triosephosphate isomerase from Giardia lamblia at functional and structural levels, providing molecular leads in the design of new antigiardiasic drugs.
Biochim Biophys Acta
; 1860(1 Pt A): 97-107, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26518348
14.
Mutations of Glucose-6-Phosphate Dehydrogenase Durham, Santa-Maria and A+ Variants Are Associated with Loss Functional and Structural Stability of the Protein.
Int J Mol Sci
; 16(12): 28657-68, 2015 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-26633385
15.
The oxidative fermentation of ethanol in Gluconacetobacter diazotrophicus is a two-step pathway catalyzed by a single enzyme: alcohol-aldehyde Dehydrogenase (ADHa).
Int J Mol Sci
; 16(1): 1293-311, 2015 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-25574602
16.
The E104D mutation increases the susceptibility of human triosephosphate isomerase to proteolysis. Asymmetric cleavage of the two monomers of the homodimeric enzyme.
Biochim Biophys Acta
; 1834(12): 2702-11, 2013 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24056040
17.
Different contribution of conserved amino acids to the global properties of triosephosphate isomerases.
Proteins
; 82(2): 323-35, 2014 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-23966267
18.
Giardial triosephosphate isomerase as possible target of the cytotoxic effect of omeprazole in Giardia lamblia.
Antimicrob Agents Chemother
; 58(12): 7072-82, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25223993
19.
The stability of G6PD is affected by mutations with different clinical phenotypes.
Int J Mol Sci
; 15(11): 21179-201, 2014 Nov 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-25407525
20.
Naturally occurring deamidated triosephosphate isomerase is a promising target for cell-selective therapy in cancer.
Sci Rep
; 12(1): 4028, 2022 03 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35256749