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1.
Metal-Free Polymer-Based Affinity Medium for Selective Purification of His6-Tagged Proteins.
Biomacromolecules
; 22(4): 1695-1705, 2021 04 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33783189
2.
Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling.
Bioorg Med Chem
; 24(10): 2215-34, 2016 05 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27085672
3.
Epitope discovery for a synthetic polymer nanoparticle: a new strategy for developing a peptide tag.
J Am Chem Soc
; 136(4): 1194-7, 2014 Jan 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-24410250
4.
The R1275Q neuroblastoma mutant and certain ATP-competitive inhibitors stabilize alternative activation loop conformations of anaplastic lymphoma kinase.
J Biol Chem
; 287(44): 37447-57, 2012 Oct 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22932897
5.
Discovery of 2,4-bis-arylamino-1,3-pyrimidines as insulin-like growth factor-1 receptor (IGF-1R) inhibitors.
Bioorg Med Chem Lett
; 21(8): 2394-9, 2011 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21414779
6.
Corrigendum to "Purinylpyridinylamino-based DFG-in/αC-helix-out B-Raf inhibitors: Applying mutant versus wild-type B-Raf selectivity indices for compound profiling" [Bioorg. Med. Chem. 24 (2016) 2215-2234].
Bioorg Med Chem
; 24(13): 3093, 2016 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27234892
7.
Structure-based design of novel 2-amino-6-phenyl-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-ones as potent and orally active inhibitors of lymphocyte specific kinase (Lck): synthesis, SAR, and in vivo anti-inflammatory activity.
J Med Chem
; 51(6): 1637-48, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18278858
8.
Structure-guided design of aminopyrimidine amides as potent, selective inhibitors of lymphocyte specific kinase: synthesis, structure-activity relationships, and inhibition of in vivo T cell activation.
J Med Chem
; 51(6): 1681-94, 2008 Mar 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-18321037
9.
N-(3-(phenylcarbamoyl)arylpyrimidine)-5-carboxamides as potent and selective inhibitors of Lck: structure, synthesis and SAR.
Bioorg Med Chem Lett
; 18(3): 1172-6, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18083554
10.
Novel 2-aminopyrimidine carbamates as potent and orally active inhibitors of Lck: synthesis, SAR, and in vivo antiinflammatory activity.
J Med Chem
; 49(16): 4981-91, 2006 Aug 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-16884310
11.
Discovery of aminoquinazolines as potent, orally bioavailable inhibitors of Lck: synthesis, SAR, and in vivo anti-inflammatory activity.
J Med Chem
; 49(19): 5671-86, 2006 Sep 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-16970394
12.
Evaluation of recombinant monoclonal antibody SVmab1 binding to Na V1.7 target sequences and block of human Na V1.7 currents.
F1000Res
; 5: 2764, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27990272
13.
The discovery and optimization of a novel class of potent, selective, and orally bioavailable anaplastic lymphoma kinase (ALK) inhibitors with potential utility for the treatment of cancer.
J Med Chem
; 55(14): 6523-40, 2012 Jul 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-22734674
14.
Selective inhibitors of the mutant B-Raf pathway: discovery of a potent and orally bioavailable aminoisoquinoline.
J Med Chem
; 52(20): 6189-92, 2009 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-19764794
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