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1.
Active site-directed double mutants of dihydrofolate reductase.
Cancer Res
; 56(18): 4142-5, 1996 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-8797582
2.
Dihydrofolate reductase protein inhibits its own translation by binding to dihydrofolate reductase mRNA sequences within the coding region.
Biochemistry
; 36(40): 12317-22, 1997 Oct 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-9315871
3.
Probing the folate-binding site of human thymidylate synthase by site-directed mutagenesis. Generation of mutants that confer resistance to raltitrexed, Thymitaq, and BW1843U89.
J Biol Chem
; 273(47): 31209-14, 1998 Nov 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-9813027
4.
Isolation and characterization of thymitaq (AG337) and 5-fluoro-2-deoxyuridylate-resistant mutants of human thymidylate synthase from ethyl methanesulfonate-exposed human sarcoma HT1080 cells.
J Biol Chem
; 273(19): 11611-8, 1998 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-9565579
5.
Variants of human dihydrofolate reductase with substitutions at leucine-22: effect on catalytic and inhibitor binding properties.
Mol Pharmacol
; 49(3): 430-7, 1996 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-8643082
6.
Use of variants of dihydrofolate reductase in gene transfer to produce resistance to methotrexate and trimetrexate.
Prog Exp Tumor Res
; 36: 82-94, 1999.
Artículo
en Inglés
| MEDLINE | ID: mdl-10386066
7.
Protection of bone marrow cells from toxicity of chemotherapeutic agents targeted toward thymidylate synthase by transfer of mutant forms of human thymidylate synthase cDNA.
Prog Exp Tumor Res
; 36: 107-14, 1999.
Artículo
en Inglés
| MEDLINE | ID: mdl-10386068
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