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1.
Allosteric modulation of an excitatory amino acid transporter: the subtype-selective inhibitor UCPH-101 exerts sustained inhibition of EAAT1 through an intramonomeric site in the trimerization domain.
J Neurosci
; 33(3): 1068-87, 2013 Jan 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-23325245
2.
Probing for improved potency and in vivo bioavailability of excitatory amino acid transporter subtype 1 inhibitors UCPH-101 and UCPH-102: design, synthesis and pharmacological evaluation of substituted 7-biphenyl analogs.
Neurochem Res
; 39(10): 1964-79, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-24682739
3.
N-Methylanilide and N-methylbenzamide derivatives as phosphodiesterase 10A (PDE10A) inhibitors.
Bioorg Med Chem
; 21(19): 6053-62, 2013 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23978358
4.
Identification of a New Class of Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitors Followed by a Structure-Activity Relationship Study.
J Med Chem
; 59(19): 8757-8770, 2016 10 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-27626828
5.
New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.
J Med Chem
; 59(3): 914-24, 2016 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26814576
6.
New Insight into the Structure-Activity Relationships of the Selective Excitatory Amino Acid Transporter Subtypeâ 1 (EAAT1) Inhibitors UCPH-101 and UCPH-102.
ChemMedChem
; 11(4): 382-402, 2016 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26757239
7.
Bioavailability Studies and inâ vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtypeâ 1 (EAAT1) Inhibitor UCPH-102.
ChemMedChem
; 11(4): 403-19, 2016 Feb 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-26797816
8.
Structure-activity relationship study of first selective inhibitor of excitatory amino acid transporter subtype 1: 2-Amino-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3-carbonitrile (UCPH-101).
J Med Chem
; 53(19): 7180-91, 2010 Oct 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-20857912
9.
Excitatory amino acid transporters as potential drug targets.
Expert Opin Ther Targets
; 13(6): 719-31, 2009 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-19456273
10.
Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1.
J Med Chem
; 52(4): 912-5, 2009 Feb 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19161278
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