Detalles de la búsqueda
1.
Visible Light Degradation of a Monoclonal Antibody in a High-Concentration Formulation: Characterization of a Tryptophan-Derived Chromophoric Photo-product by Comparison to Photo-degradation of N-Acetyl-l-tryptophan Amide.
Mol Pharm
; 18(9): 3223-3234, 2021 09 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34482697
2.
Refolding and purification of cGMP-grade recombinant human neurturin from Escherichia coli inclusion bodies.
Protein Expr Purif
; 168: 105552, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31866372
3.
Arginine to Lysine Mutations Increase the Aggregation Stability of a Single-Chain Variable Fragment through Unfolded-State Interactions.
Biochemistry
; 58(32): 3413-3421, 2019 08 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-31314511
4.
Developability Assessment of Engineered Monoclonal Antibody Variants with a Complex Self-Association Behavior Using Complementary Analytical and in Silico Tools.
Mol Pharm
; 15(12): 5697-5710, 2018 12 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30395473
5.
Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements.
Anal Chem
; 89(17): 8931-8941, 2017 09 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28753295
6.
Activated mesenchymal stem cells increase drug susceptibility of methicillin-resistant Staphylococcus aureus and Pseudomonas aeruginosa.
Folia Microbiol (Praha)
; 69(1): 145-154, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-37924430
7.
Towards more tolerable subcutaneous administration: Review of contributing factors for improving combination product design.
Adv Drug Deliv Rev
; 209: 115301, 2024 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-38570141
8.
Conformational Changes and Drivers of Monoclonal Antibody Liquid-Liquid Phase Separation.
J Pharm Sci
; 112(3): 680-690, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36306862
9.
Developability profiling of a panel of Fc engineered SARS-CoV-2 neutralizing antibodies.
MAbs
; 15(1): 2152526, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-36476037
10.
Correction to Empirical Correction for Differences in Chemical Exchange Rates in Hydrogen Exchange-Mass Spectrometry Measurements.
Anal Chem
; 89(24): 13673, 2017 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-29210567
11.
Electrostatically Driven Protein-Protein Interactions: Quantitative Prediction of Second Osmotic Virial Coefficients to Aid Antibody Design.
J Phys Chem Lett
; 13(5): 1366-1372, 2022 Feb 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-35112863
12.
The effect of PEGylation on the stability of small therapeutic proteins.
Pharm Dev Technol
; 16(5): 441-8, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21261458
13.
Global multi-method analysis of interaction parameters for reversibly self-associating macromolecules at high concentrations.
Sci Rep
; 11(1): 5741, 2021 03 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33707571
14.
Biophysical characterization of rotavirus serotypes G1, G3 and G4.
Hum Vaccin
; 6(5): 390-8, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20534978
15.
Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 2.
J Pharm Sci
; 109(1): 353-363, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31195015
16.
Characterization of Excipient Effects on Reversible Self-Association, Backbone Flexibility, and Solution Properties of an IgG1 Monoclonal Antibody at High Concentrations: Part 1.
J Pharm Sci
; 109(1): 340-352, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31201906
17.
Measuring aggregates, self-association, and weak interactions in concentrated therapeutic antibody solutions.
MAbs
; 12(1): 1810488, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32887536
18.
Cis/Trans Isomerization of Unsaturated Fatty Acids in Polysorbate 80 During Light Exposure of a Monoclonal Antibody-Containing Formulation.
J Pharm Sci
; 109(1): 603-613, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31715179
19.
Comparison of Polysorbate 80 Hydrolysis and Oxidation on the Aggregation of a Monoclonal Antibody.
J Pharm Sci
; 109(1): 633-639, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31758949
20.
Evaluation of Hydrogen Exchange Mass Spectrometry as a Stability-Indicating Method for Formulation Excipient Screening for an IgG4 Monoclonal Antibody.
J Pharm Sci
; 107(4): 1009-1019, 2018 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-29269271