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1.
Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity.
J Virol
; 96(8): e0012822, 2022 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35343766
2.
Asialoglycoprotein receptor 1 is a novel PCSK9-independent ligand of liver LDLR cleaved by furin.
J Biol Chem
; 297(4): 101177, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34508778
3.
Processing of human toll-like receptor 7 by furin-like proprotein convertases is required for its accumulation and activity in endosomes.
Immunity
; 39(4): 711-21, 2013 Oct 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24138882
4.
Ser-Phosphorylation of PCSK9 (Proprotein Convertase Subtilisin-Kexin 9) by Fam20C (Family With Sequence Similarity 20, Member C) Kinase Enhances Its Ability to Degrade the LDLR (Low-Density Lipoprotein Receptor).
Arterioscler Thromb Vasc Biol
; 39(10): 1996-2013, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31553664
5.
Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
J Biol Chem
; 292(25): 10564-10573, 2017 06 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-28468828
6.
The Proprotein Convertase Subtilisin/Kexin Type 9-resistant R410S Low Density Lipoprotein Receptor Mutation: A NOVEL MECHANISM CAUSING FAMILIAL HYPERCHOLESTEROLEMIA.
J Biol Chem
; 292(5): 1573-1590, 2017 02 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-27998977
7.
A single domain antibody against the Cys- and His-rich domain of PCSK9 and evolocumab exhibit different inhibition mechanisms in humanized PCSK9 mice.
Biol Chem
; 399(12): 1363-1374, 2018 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30044755
8.
Erratum for Essalmani et al., "Distinctive Roles of Furin and TMPRSS2 in SARS-CoV-2 Infectivity".
J Virol
; 96(13): e0074522, 2022 Jul 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-35658532
9.
An Unbiased Mass Spectrometry Approach Identifies Glypican-3 as an Interactor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) in Hepatocellular Carcinoma Cells.
J Biol Chem
; 291(47): 24676-24687, 2016 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-27758865
10.
Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Single Domain Antibodies Are Potent Inhibitors of Low Density Lipoprotein Receptor Degradation.
J Biol Chem
; 291(32): 16659-71, 2016 08 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-27284008
11.
Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other.
J Biol Chem
; 290(30): 18609-20, 2015 Jul 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-26085104
12.
Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.
Proc Natl Acad Sci U S A
; 110(43): 17362-7, 2013 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-24101515
13.
PCSK9 deficiency unmasks a sex- and tissue-specific subcellular distribution of the LDL and VLDL receptors in mice.
J Lipid Res
; 56(11): 2133-42, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-26323289
14.
Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.
J Biol Chem
; 288(37): 26410-8, 2013 Sep 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23918928
15.
Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.
Hepatology
; 57(6): 2514-24, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23390091
16.
Insights into PCSK9-LDLR Regulation and Trafficking via the Differential Functions of MHC-I Proteins HFE and HLA-C.
Cells
; 13(10)2024 May 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-38786080
17.
PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.
Metabolism
; 150: 155736, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37967646
18.
Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
J Biol Chem
; 292(33): 13565, 2017 08 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-28821605
19.
SKI-1/S1P Facilitates SARS-CoV-2 Spike Induced Cell-to-Cell Fusion via Activation of SREBP-2 and Metalloproteases, Whereas PCSK9 Enhances the Degradation of ACE2.
Viruses
; 15(2)2023 01 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36851576
20.
Latent transforming growth factor beta-binding proteins-2 and -3 inhibit the proprotein convertase 5/6A.
J Biol Chem
; 286(33): 29063-29073, 2011 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-21700711