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1.
Implementation of a LC-MS based multi-attribute method (MAM) and intact multi-attribute method (iMAM) workflow for the characterisation of a GLP-Fc fusion protein.
Anal Biochem
; : 115585, 2024 Jun 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38851475
2.
A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency.
Int J Mol Sci
; 25(5)2024 Feb 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-38474031
3.
Exploring Charge-Detection Mass Spectrometry on Chromatographic Time Scales.
Anal Chem
; 95(40): 15118-15124, 2023 10 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37772750
4.
Rapid Analysis of Biotherapeutics Using Protein A Chromatography Coupled to Orbitrap Mass Spectrometry.
Anal Chem
; 93(40): 13505-13512, 2021 10 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34585915
5.
A Native Mass Spectrometry-Based Assay for Rapid Assessment of the Empty:Full Capsid Ratio in Adeno-Associated Virus Gene Therapy Products.
Anal Chem
; 93(38): 12817-12821, 2021 09 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-34519199
6.
Comparative Elucidation of Cetuximab Heterogeneity on the Intact Protein Level by Cation Exchange Chromatography and Capillary Electrophoresis Coupled to Mass Spectrometry.
Anal Chem
; 92(7): 5431-5438, 2020 04 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32105056
7.
Cracking Proteoform Complexity of Ovalbumin with Anion-Exchange Chromatography-High-Resolution Mass Spectrometry under Native Conditions.
J Proteome Res
; 18(10): 3689-3702, 2019 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31478673
8.
Charge Variant Analysis of Monoclonal Antibodies Using Direct Coupled pH Gradient Cation Exchange Chromatography to High-Resolution Native Mass Spectrometry.
Anal Chem
; 90(7): 4669-4676, 2018 04 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29494133
9.
Cation exchange chromatography on a monodisperse 3 µm particle enables extensive analytical similarity assessment of biosimilars.
J Pharm Biomed Anal
; 234: 115534, 2023 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37343453
10.
Mass spectrometry friendly pH-gradient anion exchange chromatography for the separation of full and empty adeno-associated virus (AAV) capsids.
Anal Methods
; 15(43): 5788-5792, 2023 11 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37870407
11.
Exploring proteoforms of the IgG2 monoclonal antibody panitumumab using microchip capillary electrophoresis-mass spectrometry.
J Pharm Biomed Anal
; 234: 115494, 2023 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-37300951
12.
Intact multi-attribute method (iMAM): A flexible tool for the analysis of monoclonal antibodies.
Eur J Pharm Biopharm
; 177: 241-248, 2022 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-35840072
13.
Correlative N-glycan and charge variant analysis of cetuximab expressed in murine, chinese hamster and human expression systems.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1194: 123186, 2022 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35240429
14.
Native LC-MS for capturing quality attributes of biopharmaceuticals on the intact protein level.
Curr Opin Biotechnol
; 71: 32-40, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34157600
15.
Optimisation of the use of sliding window deconvolution for comprehensive characterisation of trastuzumab and adalimumab charge variants by native high resolution mass spectrometry.
Eur J Pharm Biopharm
; 158: 83-95, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33212184
16.
Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition LC-MS/MS.
J Pharm Anal
; 11(6): 726-731, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-35028177
17.
Simultaneous monitoring of multiple attributes of pyrrolobenzodiazepine antibody-drug conjugates by size exclusion chromatography - high resolution mass spectrometry.
J Pharm Biomed Anal
; 205: 114287, 2021 Oct 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-34385015
18.
Comprehensive characterisation of the heterogeneity of adalimumab via charge variant analysis hyphenated on-line to native high resolution Orbitrap mass spectrometry.
MAbs
; 11(1): 116-128, 2019 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30296204
19.
Rapid charge variant analysis of monoclonal antibodies to support lead candidate biopharmaceutical development.
J Chromatogr B Analyt Technol Biomed Life Sci
; 1095: 166-176, 2018 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30077097
20.
Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition LC-MS/MS / 药物分析学报
Journal of Pharmaceutical Analysis
; (6): 726-731, 2021.
Artículo
en Zh
| WPRIM | ID: wpr-931216
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