Detalles de la búsqueda
1.
Thymic lymphoma detection in RORγ knockout mice using 5-hydroxymethylcytosine profiling of circulating cell-free DNA.
Toxicol Appl Pharmacol
; 473: 116582, 2023 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37295732
2.
A Biomarker-Centric Approach to Drug Discovery and Development: Lessons Learned from the Coronavirus Disease 2019 Pandemic.
J Pharmacol Exp Ther
; 376(1): 12-20, 2021 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33115823
3.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) alters hepatic polyunsaturated fatty acid metabolism and eicosanoid biosynthesis in female Sprague-Dawley rats.
Toxicol Appl Pharmacol
; 398: 115034, 2020 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32387183
4.
Comparison of Hepatic NRF2 and Aryl Hydrocarbon Receptor Binding in 2,3,7,8-Tetrachlorodibenzo-p-dioxin-Treated Mice Demonstrates NRF2-Independent PKM2 Induction.
Mol Pharmacol
; 94(2): 876-884, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29752288
5.
2,3,7,8-Tetrachlorodibenzo-p-dioxin dose-dependently increases bone mass and decreases marrow adiposity in juvenile mice.
Toxicol Appl Pharmacol
; 348: 85-98, 2018 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29673856
6.
Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBα/ß activation in aryl hydrocarbon receptor-elicited hepatotoxicity.
Toxicol Appl Pharmacol
; 321: 1-17, 2017 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28213091
7.
Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo-p-dioxin.
Chem Res Toxicol
; 30(4): 1060-1075, 2017 04 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-28238261
8.
Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis.
Am J Physiol Gastrointest Liver Physiol
; 310(9): G726-38, 2016 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26968211
9.
RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice.
BMC Genomics
; 16: 373, 2015 May 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-25958198
10.
Western blotting: evolution of an old analytical method to a new quantitative tool for biomarker measurements.
Bioanalysis
; 16(5): 319-328, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38348662
11.
Absence of functional deficits in rats following systemic administration of an AAV9 vector despite moderate peripheral nerve and dorsal root ganglia findings: A clinically silent peripheral neuropathy.
Neurotoxicology
; 101: 46-53, 2024 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-38316190
12.
Consequences of reprogramming acetyl-CoA metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin in the mouse liver.
Sci Rep
; 13(1): 4138, 2023 03 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-36914879
13.
Circulating neurofilament light chain as a promising biomarker of AAV-induced dorsal root ganglia toxicity in nonclinical toxicology species.
Mol Ther Methods Clin Dev
; 25: 264-277, 2022 Jun 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-35505662
14.
Single-Nuclei RNA Sequencing Assessment of the Hepatic Effects of 2,3,7,8-Tetrachlorodibenzo-p-dioxin.
Cell Mol Gastroenterol Hepatol
; 11(1): 147-159, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-32791302
15.
Thioesterase induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin results in a futile cycle that inhibits hepatic ß-oxidation.
Sci Rep
; 11(1): 15689, 2021 08 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-34344994
16.
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice.
Sci Rep
; 10(1): 14831, 2020 09 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32908189
17.
2,3,7,8-Tetrachlorodibenzo-p-dioxin abolishes circadian regulation of hepatic metabolic activity in mice.
Sci Rep
; 9(1): 6514, 2019 04 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-31015483
18.
Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL/6 Mice.
Sci Rep
; 9(1): 15828, 2019 11 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31676775
19.
Beyond the Aryl Hydrocarbon Receptor: Pathway Interactions in the Hepatotoxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin and Related Compounds.
Curr Opin Toxicol
; 2: 36-41, 2017 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-28948239
20.
Loss of liver-specific and sexually dimorphic gene expression by aryl hydrocarbon receptor activation in C57BL/6 mice.
PLoS One
; 12(9): e0184842, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28922406