Detalles de la búsqueda
1.
Discovery process and pharmacological characterization of a novel dual orexin 1 and orexin 2 receptor antagonist useful for treatment of sleep disorders.
Bioorg Med Chem Lett
; 21(18): 5562-7, 2011 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21831639
2.
5-{2-[4-(2-methyl-5-quinolinyl)-1-piperazinyl]ethyl}-2(1H)-quinolinones and 3,4-dihydro-2(1H)-quinolinones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors. Part 3.
Bioorg Med Chem Lett
; 20(23): 7092-6, 2010 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-20951584
3.
8-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors--part II.
Bioorg Med Chem Lett
; 19(8): 2338-42, 2009 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-19286377
4.
6-[2-(4-Aryl-1-piperazinyl)ethyl]-2H-1,4-benzoxazin-3(4H)-ones: dual-acting 5-HT1 receptor antagonists and serotonin reuptake inhibitors.
Bioorg Med Chem Lett
; 18(20): 5653-6, 2008 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18799312
5.
SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4'-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain.
Neuropharmacology
; 51(3): 566-77, 2006 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-16846620
6.
SB-649915, a novel, potent 5-HT1A and 5-HT1B autoreceptor antagonist and 5-HT re-uptake inhibitor in native tissue.
Eur J Pharmacol
; 536(1-2): 54-61, 2006 Apr 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-16571351
7.
Stereoselective synthesis and preliminary evaluation of (+)- and (-)-3-methyl-5-carboxy-thien-2-yl-glycine (3-MATIDA): identification of (+)-3-MATIDA as a novel mGluR1 competitive antagonist.
Farmaco
; 59(2): 93-9, 2004 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-14871500
8.
2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: an exploration of the role of the pyrrolic scaffold.
Farmaco
; 58(10): 1005-9, 2003 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-14505730
9.
Functional and binding kinetic studies make a distinction between OX1 and OX2 orexin receptor antagonists.
Eur J Pharmacol
; 692(1-3): 1-9, 2012 Oct 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-22796453
10.
From pyrroles to pyrrolo[1,2-a]pyrazinones: a new class of mGluR1 antagonists.
Bioorg Med Chem Lett
; 16(5): 1342-5, 2006 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-16337118
11.
Evidence that the metabotropic glutamate receptor 5 antagonist MPEP may act as an inhibitor of the norepinephrine transporter in vitro and in vivo.
Synapse
; 50(4): 269-76, 2003 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-14556231
12.
2,4-Dicarboxy-pyrroles as selective non-competitive mGluR1 antagonists: further characterization of 3,5-dimethyl pyrrole-2,4-dicarboxylic acid 2-propyl ester 4-(1,2,2-trimethyl-propyl) ester and structure-activity relationships.
Bioorg Med Chem Lett
; 13(13): 2113-8, 2003 Jul 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-12798316
Resultados
1 -
12
de 12
1
Próxima >
>>