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1.
Imparting aromaticity to 2-pyridone derivatives by O-alkylation resulted in new competitive and non-competitive PIM-1 kinase inhibitors with caspase-activated apoptosis.
J Enzyme Inhib Med Chem
; 39(1): 2304044, 2024 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-38230430
2.
Discovery of new pyridine-quinoline hybrids as competitive and non-competitive PIM-1 kinase inhibitors with apoptosis induction and caspase 3/7 activation capabilities.
J Enzyme Inhib Med Chem
; 38(1): 2152810, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36629075
3.
Design and synthesis of 2-Substituted-4-benzyl-5-methylimidazoles as new potential Anti-breast cancer agents to inhibit oncogenic STAT3 functions.
Bioorg Chem
; 113: 105033, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34089945
4.
Synthesis, modeling and biological evaluation of some pyrazolo[3,4-d]pyrimidinones and pyrazolo[4,3-e][1,2,4]triazolo[4,3-a]pyrimidinones as anti-inflammatory agents.
Bioorg Chem
; 90: 102844, 2019 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-31229797
5.
Design, synthesis and docking study of pyridine and thieno[2,3-b] pyridine derivatives as anticancer PIM-1 kinase inhibitors.
Bioorg Chem
; 80: 674-692, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-30064079
6.
Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidine derivatives bearing thiazolidinone moiety as anti-inflammatory agents.
Bioorg Chem
; 80: 164-173, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29929077
7.
Design, synthesis and evaluation of some pyrazolo[3,4-d]pyrimidines as anti-inflammatory agents.
Bioorg Chem
; 78: 358-371, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29627656
8.
Synthesis, in silico experiments and biological evaluation of 1,3,4-trisubstituted pyrazole derivatives as antimalarial agents.
Eur J Med Chem
; 163: 353-366, 2019 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30530172
9.
Synthesis, molecular modeling and biological screening of some pyrazole derivatives as antileishmanial agents.
Future Med Chem
; 10(19): 2325-2344, 2018 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30215271
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