Detalles de la búsqueda
1.
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer.
Nature
; 578(7794): 306-310, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31969702
2.
Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Nature
; 558(7710): E1, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29769713
3.
Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.
Nature
; 550(7674): 128-132, 2017 10 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28953875
4.
Selective Inhibition of the Second Bromodomain of BET Family Proteins Results in Robust Antitumor Activity in Preclinical Models of Acute Myeloid Leukemia.
Mol Cancer Ther
; 20(10): 1809-1819, 2021 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-34253595
5.
Progesterone receptors upregulate Wnt-1 to induce epidermal growth factor receptor transactivation and c-Src-dependent sustained activation of Erk1/2 mitogen-activated protein kinase in breast cancer cells.
Mol Cell Biol
; 27(2): 466-80, 2007 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-17074804
6.
Discovery of N-Ethyl-4-[2-(4-fluoro-2,6-dimethyl-phenoxy)-5-(1-hydroxy-1-methyl-ethyl)phenyl]-6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridine-2-carboxamide (ABBV-744), a BET Bromodomain Inhibitor with Selectivity for the Second Bromodomain.
J Med Chem
; 63(10): 5585-5623, 2020 05 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32324999
7.
Scaffolding actions of membrane-associated progesterone receptors.
Steroids
; 74(7): 568-72, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19135465
8.
Progesterone receptor rapid signaling mediates serine 345 phosphorylation and tethering to specificity protein 1 transcription factors.
Mol Endocrinol
; 22(4): 823-37, 2008 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-18202149
9.
Phosphorylation-dependent antagonism of sumoylation derepresses progesterone receptor action in breast cancer cells.
Mol Endocrinol
; 21(12): 2890-906, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17717077
10.
Linkage of progestin and epidermal growth factor signaling: phosphorylation of progesterone receptors mediates transcriptional hypersensitivity and increased ligand-independent breast cancer cell growth.
Steroids
; 72(2): 188-201, 2007 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-17173941
11.
Exploitation of Castration-Resistant Prostate Cancer Transcription Factor Dependencies by the Novel BET Inhibitor ABBV-075.
Mol Cancer Res
; 15(1): 35-44, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27707886
12.
Vulnerability of Small-Cell Lung Cancer to Apoptosis Induced by the Combination of BET Bromodomain Proteins and BCL2 Inhibitors.
Mol Cancer Ther
; 16(8): 1511-1520, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28468776
13.
Preclinical Characterization of BET Family Bromodomain Inhibitor ABBV-075 Suggests Combination Therapeutic Strategies.
Cancer Res
; 77(11): 2976-2989, 2017 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28416490
14.
Discovery of N-(4-(2,4-Difluorophenoxy)-3-(6-methyl-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)phenyl)ethanesulfonamide (ABBV-075/Mivebresib), a Potent and Orally Available Bromodomain and Extraterminal Domain (BET) Family Bromodomain Inhibitor.
J Med Chem
; 60(20): 8369-8384, 2017 10 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-28949521
15.
Progesterone receptors induce cell cycle progression via activation of mitogen-activated protein kinases.
Mol Endocrinol
; 19(2): 327-39, 2005 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-15486045
16.
Integration of progesterone receptor mediated rapid signaling and nuclear actions in breast cancer cell models: role of mitogen-activated protein kinases and cell cycle regulators.
Steroids
; 70(5-7): 418-26, 2005.
Artículo
en Inglés
| MEDLINE | ID: mdl-15862825
17.
Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors.
Mol Endocrinol
; 17(4): 628-42, 2003 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-12554776
18.
A gene-expression screen identifies a non-toxic sumoylation inhibitor that mimics SUMO-less human LRH-1 in liver.
Elife
; 42015 Dec 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-26653140
19.
Cross-talk between growth factor and progesterone receptor signaling pathways: implications for breast cancer cell growth.
Breast Dis
; 18: 21-31, 2003.
Artículo
en Inglés
| MEDLINE | ID: mdl-15687686
20.
Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development.
Dev Cell
; 21(2): 315-27, 2011 Aug 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-21820362