Detalles de la búsqueda
1.
Targeting the Protein Tunnels of the Urease Accessory Complex: A Theoretical Investigation.
Molecules
; 25(12)2020 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32599898
2.
Structure-Based Virtual Screening Allows the Identification of Efficient Modulators of E-Cadherin-Mediated Cell-Cell Adhesion.
Int J Mol Sci
; 20(14)2019 Jul 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31373305
3.
Development of a multisite model for Ni(II) ion in solution from thermodynamic and kinetic data.
J Comput Chem
; 38(21): 1834-1843, 2017 06 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28558120
4.
Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification.
Anal Chem
; 88(19): 9510-9517, 2016 10 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-27583774
5.
Synthesis of natural urolithin M6, a galloflavin mimetic, as a potential inhibitor of lactate dehydrogenase A.
Org Biomol Chem
; 14(46): 10981-10987, 2016 11 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-27827510
6.
From AChE to BACE1 inhibitors: The role of the amine on the indanone scaffold.
Bioorg Med Chem Lett
; 25(14): 2804-8, 2015 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26003339
7.
Probing allosteric communication with combined molecular dynamics simulations and network analysis.
Curr Opin Struct Biol
; 86: 102820, 2024 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38688074
8.
Collecting and assessing human lactate dehydrogenase-A conformations for structure-based virtual screening.
J Chem Inf Model
; 53(11): 2792-7, 2013 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-24138094
9.
Innovative Strategy toward Mutant CFTR Rescue in Cystic Fibrosis: Design and Synthesis of Thiadiazole Inhibitors of the E3 Ligase RNF5.
J Med Chem
; 66(14): 9797-9822, 2023 07 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-37440686
10.
Discovery of the first small molecule inhibitor of human DDX3 specifically designed to target the RNA binding site: towards the next generation HIV-1 inhibitors.
Bioorg Med Chem Lett
; 22(5): 2094-8, 2012 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22300661
11.
A combined targeted/phenotypic approach for the identification of new antiangiogenics agents active on a zebrafish model: from in silico screening to cyclodextrin formulation.
Bioorg Med Chem Lett
; 22(17): 5579-83, 2012 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22853993
12.
Proteostasis Regulators in Cystic Fibrosis: Current Development and Future Perspectives.
J Med Chem
; 65(7): 5212-5243, 2022 04 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-35377645
13.
Computational techniques are valuable tools for the discovery of protein-protein interaction inhibitors: the 14-3-3σ case.
Bioorg Med Chem Lett
; 21(22): 6867-71, 2011 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-21962576
14.
Divide et impera: An In Silico Screening Targeting HCMV ppUL44 Processivity Factor Homodimerization Identifies Small Molecules Inhibiting Viral Replication.
Viruses
; 13(5)2021 05 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34065234
15.
Searching for New Microbiome-Targeted Therapeutics through a Drug Repurposing Approach.
J Med Chem
; 64(23): 17277-17286, 2021 12 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34846885
16.
Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib.
J Med Chem
; 63(5): 2588-2619, 2020 03 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-32037829
17.
Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells.
Eur J Med Chem
; 165: 80-92, 2019 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30660828
18.
N-(thiazol-2-yl)-2-thiophene carboxamide derivatives as Abl inhibitors identified by a pharmacophore-based database screening of commercially available compounds.
Bioorg Med Chem Lett
; 18(15): 4328-31, 2008 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18621522
19.
Discovery and SAR of 1,3,4-thiadiazole derivatives as potent Abl tyrosine kinase inhibitors and cytodifferentiating agents.
Bioorg Med Chem Lett
; 18(3): 1207-11, 2008 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-18078752
20.
Radial access for percutaneous coronary procedure: relationship between operator expertise and complications.
Clin Exp Emerg Med
; 5(2): 95-99, 2018 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-29973034