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1.
Etanercept ameliorates inflammation and pain in a novel mono-arthritic multi-flare model of streptococcal cell wall induced arthritis.
BMC Musculoskelet Disord
; 15: 409, 2014 Dec 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-25477192
2.
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease.
J Med Chem
; 66(21): 14912-14927, 2023 11 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-37861679
3.
Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors.
J Med Chem
; 65(1): 838-856, 2022 01 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-34967623
4.
Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1-Heteroaryl-1H-Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson's Disease.
J Med Chem
; 65(24): 16801-16817, 2022 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36475697
5.
Optimization of brain-penetrant picolinamide derived leucine-rich repeat kinase 2 (LRRK2) inhibitors.
RSC Med Chem
; 12(7): 1164-1173, 2021 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-34355182
6.
Development and optimization of a high-throughput micro-computed tomography imaging method incorporating a novel analysis technique to evaluate bone mineral density of arthritic joints in a rodent model of collagen induced arthritis.
Bone
; 73: 32-41, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-25482211
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