Detalles de la búsqueda
1.
The novel CDK9 inhibitor, XPW1, alone and in combination with BRD4 inhibitor JQ1, for the treatment of clear cell renal cell carcinoma.
Br J Cancer
; 129(12): 1915-1929, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37884683
2.
Design, synthesis, and biological evaluation of carbonyl-hydrazine-1-carboxamide derivatives as anti-hepatic fibrosis agents targeting Nur77.
Bioorg Chem
; 140: 106795, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37657195
3.
Discovery of new DHA ethanolamine derivatives as potential anti-inflammatory agents targeting Nur77.
Bioorg Chem
; 141: 106887, 2023 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-37801784
4.
Design, synthesis, and evaluation of novel benzoylhydrazone derivatives as Nur77 modulators with potent antitumor activity against hepatocellular carcinoma.
J Enzyme Inhib Med Chem
; 38(1): 2227777, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37357764
5.
Approved Small-Molecule ATP-Competitive Kinases Drugs Containing Indole/Azaindole/Oxindole Scaffolds: R&D and Binding Patterns Profiling.
Molecules
; 28(3)2023 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-36770611
6.
Design and synthesis of N-(1-(6-(substituted phenyl)-pyridazin-3-yl)-piperidine-3-yl)-amine derivatives as JMJD6 inhibitors.
Bioorg Chem
; 129: 106119, 2022 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36116323
7.
Design and synthesis of adamantyl-substituted flavonoid derivatives as anti-inflammatory Nur77 modulators: Compound B7 targets Nur77 and improves LPS-induced inflammation in vitro and in vivo.
Bioorg Chem
; 120: 105645, 2022 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-35121551
8.
Discovery of a Nur77-mediated cytoplasmic vacuolation and paraptosis inducer (4-PQBH) for the treatment of hepatocellular carcinoma.
Bioorg Chem
; 121: 105651, 2022 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35182885
9.
Synthesis, SAR study, and bioactivity evaluation of a series of Quinoline-Indole-Schiff base derivatives: Compound 10E as a new Nur77 exporter and autophagic death inducer.
Bioorg Chem
; 113: 105008, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34089944
10.
Discovery of new chalone adamantyl arotinoids having RXRα-modulating and anticancer activities.
Bioorg Chem
; 113: 104961, 2021 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34023650
11.
Design, synthesis, and biological evaluation of 5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-Indole-2-Carbohydrazide derivatives: the methuosis inducer 12A as a Novel and selective anticancer agent.
J Enzyme Inhib Med Chem
; 36(1): 1436-1453, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34229558
12.
Synthesis and Antiproliferative Activity of New Thiosemicarboxamide Derivatives.
Chem Biodivers
; 18(12): e2100671, 2021 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-34738709
13.
Glycine metabolomic changes induced by anticancer agents in A549 cells.
Amino Acids
; 52(5): 793-809, 2020 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-32430875
14.
Synthesis and discovery of ω-3 polyunsaturated fatty acid- alkanolamine (PUFA-AA) derivatives as anti-inflammatory agents targeting Nur77.
Bioorg Chem
; 105: 104456, 2020 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33217634
15.
Design, synthesis and biological evaluation of methylenehydrazine-1-carboxamide derivatives with (5-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)-1H-indole scaffold: Novel potential CDK9 inhibitors.
Bioorg Chem
; 102: 104064, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32653610
16.
Synthesis and biological evaluations of N'-substituted methylene-4-(quinoline-4-amino) benzoylhydrazides as potential anti-hepatoma agents.
Bioorg Chem
; 96: 103592, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32044517
17.
Synthesis and biological evaluation of (3/4-(pyrimidin-2-ylamino)benzoyl)-based hydrazine-1-carboxamide/carbothioamide derivatives as novel RXRα antagonists.
J Enzyme Inhib Med Chem
; 35(1): 880-896, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32223461
18.
Synthesis, biological activities, and docking studies of d-pantolactone derivatives as novel FAS inhibitors.
Bioorg Med Chem
; 27(20): 115069, 2019 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-31492533
19.
Two New Cytotoxic Compounds from a Deep-Sea Penicillum citreonigrum XT20-134.
Mar Drugs
; 17(9)2019 Aug 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-31470583
20.
Cobalt-Catalyzed Oxidative C(sp3)-H Phosphonylation for α-Aminophosphonates via C(sp3)-H/P(O)-H Coupling.
J Org Chem
; 83(12): 6754-6761, 2018 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-29786437