Búsqueda | Biblioteca Virtual en Salud

1.

Therapeutic efficacy of FASN inhibition in preclinical models of HCC.

Wang, Haichuan; Zhou, Yi; Xu, Hongwei; Wang, Xue; Zhang, Yi; Shang, Runze; O'Farrell, Marie; Roessler, Stephanie; Sticht, Carsten; Stahl, Andreas; Evert, Matthias; Calvisi, Diego F; Zeng, Yong; Chen, Xin.

Hepatology ; 76(4): 951-966, 2022 10.

Artículo en Inglés | MEDLINE | ID: mdl-35076948

2.

TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial.

Loomba, Rohit; Mohseni, Rizwana; Lucas, K Jean; Gutierrez, Julio A; Perry, Robert G; Trotter, James F; Rahimi, Robert S; Harrison, Stephen A; Ajmera, Veeral; Wayne, Jeffrey D; O'Farrell, Marie; McCulloch, William; Grimmer, Katharine; Rinella, Mary; Wai-Sun Wong, Vincent; Ratziu, Vlad; Gores, Gregory J; Neuschwander-Tetri, Brent A; Kemble, George.

Gastroenterology ; 161(5): 1475-1486, 2021 11.

Artículo en Inglés | MEDLINE | ID: mdl-34310978

3.

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.

Worthmann, Anna; Ridder, Julius; Piel, Sharlaine Y L; Evangelakos, Ioannis; Musfeldt, Melina; Voß, Hannah; O'Farrell, Marie; Fischer, Alexander W; Adak, Sangeeta; Sundd, Monica; Siffeti, Hasibullah; Haumann, Friederike; Kloth, Katja; Bierhals, Tatjana; Heine, Markus; Pertzborn, Paul; Pauly, Mira; Scholz, Julia-Josefine; Kundu, Suman; Fuh, Marceline M; Neu, Axel; Tödter, Klaus; Hempel, Maja; Knippschild, Uwe; Semenkovich, Clay F; Schlüter, Hartmut; Heeren, Joerg; Scheja, Ludger; Kubisch, Christian; Schlein, Christian.

Nat Commun ; 15(1): 45, 2024 01 02.

Artículo en Inglés | MEDLINE | ID: mdl-38167725

4.

Towards an extensive set of criteria for safety and cyber-security evaluation of cyber-physical systems.

Smrcka, Ales; Sangchoolie, Behrooz; Mingozzi, Emanuele; de la Vara, Jose Luis; Farrell, Marie; Barbosa, Raul; Baglum, Cem; Yayan, Ugur; Ergun, Salih; Kanak, Alper.

Open Res Eur ; 3: 219, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-38645797

5.

Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy.

Talebi, Ali; de Laat, Vincent; Spotbeen, Xander; Dehairs, Jonas; Rambow, Florian; Rogiers, Aljosja; Vanderhoydonc, Frank; Rizotto, Lara; Planque, Mélanie; Doglioni, Ginevra; Motamedi, Sahar; Nittner, David; Roskams, Tania; Agostinis, Patrizia; Bechter, Oliver; Boecxstaens, Veerle; Garmyn, Marjan; O'Farrell, Marie; Wagman, Alan; Kemble, George; Leucci, Eleonora; Fendt, Sarah-Maria; Marine, Jean-Christophe; Swinnen, Johannes V.

J Exp Clin Cancer Res ; 42(1): 92, 2023 Apr 19.

Artículo en Inglés | MEDLINE | ID: mdl-37072838

6.

FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models.

O'Farrell, Marie; Duke, Greg; Crowley, Richard; Buckley, Douglas; Martins, Eduardo B; Bhattacharya, Dipankar; Friedman, Scott L; Kemble, George.

Sci Rep ; 12(1): 15661, 2022 09 19.

Artículo en Inglés | MEDLINE | ID: mdl-36123383

7.

Formal Modelling and Runtime Verification of Autonomous Grasping for Active Debris Removal.

Farrell, Marie; Mavrakis, Nikos; Ferrando, Angelo; Dixon, Clare; Gao, Yang.

Front Robot AI ; 8: 639282, 2021.

Artículo en Inglés | MEDLINE | ID: mdl-35155585

8.

First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors.

Falchook, Gerald; Infante, Jeffrey; Arkenau, Hendrik-Tobias; Patel, Manish R; Dean, Emma; Borazanci, Erkut; Brenner, Andrew; Cook, Natalie; Lopez, Juanita; Pant, Shubham; Frankel, Arthur; Schmid, Peter; Moore, Kathleen; McCulloch, William; Grimmer, Katharine; O'Farrell, Marie; Kemble, George; Burris, Howard.

EClinicalMedicine ; 34: 100797, 2021 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-33870151

9.

A replication study of priorities and attitudes of two nursing programs' communities of interest: an appreciative inquiry.

Farrell, Marie; Wallis, Nancy C; Evans, Marci Tyler.

J Prof Nurs ; 23(5): 267-77, 2007.

Artículo en Inglés | MEDLINE | ID: mdl-17903785

10.

Fatty acid synthase - Modern tumor cell biology insights into a classical oncology target.

Buckley, Douglas; Duke, Gregory; Heuer, Timothy S; O'Farrell, Marie; Wagman, Allan S; McCulloch, William; Kemble, George.

Pharmacol Ther ; 177: 23-31, 2017 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-28202364

11.

Exploring and developing a college's community of interest: an appreciative inquiry.

Farrell, Marie; Douglas, Dianna; Siltanen, Susan.

J Prof Nurs ; 19(6): 364-71, 2003.

Artículo en Inglés | MEDLINE | ID: mdl-14689393

12.

p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

Chow, Hoi Yee; Jubb, Adrian M; Koch, Jennifer N; Jaffer, Zahara M; Stepanova, Dina; Campbell, David A; Duron, Sergio G; O'Farrell, Marie; Cai, Kathy Q; Klein-Szanto, Andres J P; Gutkind, J Silvio; Hoeflich, Klaus P; Chernoff, Jonathan.

Cancer Res ; 72(22): 5966-75, 2012 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-22983922

13.

Evaluating the chief nurse executive: reflections on the process.

Farrell, Marie P.

J Nurs Adm ; 34(10): 458-62, 2004 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-15577668

14.

Pushing for progress

Farrell, Marie P..

Artículo en Inglés | WHOLIS | ID: who-51761

15.

La pugna por el progreso

Farrell, Marie P..

Artículo en Español | WHOLIS | ID: who-47984

16.

Aller de l'avant

Farrell, Marie P..

Artículo en Francés | WHOLIS | ID: who-45060

17.

First Joint Planning Meeting for Plan of Work following the earthquaKe in Armenian SSR, USSR : Report of a meeting

Farrell, Marie; Jones, John.

Copenhagen; World Health Organization; 1989. (130) p. tab. (EUR/SSR/COR 001 0447r).

No convencional en En | Desastres | ID: des-839

18.

Work Programme for Rehabilitation following the Earthquake in Armenian SSR, USSR

Rochon, J; Tsechkovski, M; Espinoza, O; Farrell, Marie; Jones, John.

s.l; s.n; 9 Feb. 1989. 23 p.

No convencional en En | Desastres | ID: des-210

19.

Health research: a community-based approach

Bhaduri, Aparna; Farrell, Marie.

New Delhi; WHO Regional Office for South-East Asia; 1981. (Regional Publication No. 12).

en Inglés | WHOLIS | ID: who-205250

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Therapeutic efficacy of FASN inhibition in preclinical models of HCC.

TVB-2640 (FASN Inhibitor) for the Treatment of Nonalcoholic Steatohepatitis: FASCINATE-1, a Randomized, Placebo-Controlled Phase 2a Trial.

Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.

Towards an extensive set of criteria for safety and cyber-security evaluation of cyber-physical systems.

Pharmacological induction of membrane lipid poly-unsaturation sensitizes melanoma to ROS inducers and overcomes acquired resistance to targeted therapy.

FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models.

Formal Modelling and Runtime Verification of Autonomous Grasping for Active Debris Removal.

First-in-human study of the safety, pharmacokinetics, and pharmacodynamics of first-in-class fatty acid synthase inhibitor TVB-2640 alone and with a taxane in advanced tumors.

A replication study of priorities and attitudes of two nursing programs' communities of interest: an appreciative inquiry.

Fatty acid synthase - Modern tumor cell biology insights into a classical oncology target.

Exploring and developing a college's community of interest: an appreciative inquiry.

p21-Activated kinase 1 is required for efficient tumor formation and progression in a Ras-mediated skin cancer model.

Evaluating the chief nurse executive: reflections on the process.

Pushing for progress

La pugna por el progreso

Aller de l'avant

First Joint Planning Meeting for Plan of Work following the earthquaKe in Armenian SSR, USSR : Report of a meeting

Work Programme for Rehabilitation following the Earthquake in Armenian SSR, USSR

Health research: a community-based approach