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1.
Structural insights into the interaction of three Y-shaped ligands with PI3Kα.
Proc Natl Acad Sci U S A
; 120(34): e2304071120, 2023 08 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-37585458
2.
Cross-reactivity to glutamate carboxypeptidase III causes undesired salivary gland and kidney uptake of PSMA-targeted small-molecule radionuclide therapeutics.
Eur J Nucl Med Mol Imaging
; 50(3): 957-961, 2023 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-36184692
3.
Affinity Selections of DNA-Encoded Chemical Libraries on Carbonic Anhydrase IX-Expressing Tumor Cells Reveal a Dependence on Ligand Valence.
Chemistry
; 27(35): 8985-8993, 2021 Jun 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-33905156
4.
Large screening of DNA-compatible reaction conditions for Suzuki and Sonogashira cross-coupling reactions and for reverse amide bond formation.
Bioorg Med Chem
; 41: 116206, 2021 07 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34038862
5.
Complexation with a Cognate Antibody Fragment Facilitates Affinity Measurements of Fluorescein-Linked Small Molecule Ligands.
Anal Chem
; 92(15): 10822-10829, 2020 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32615755
6.
Comparative evaluation of DNA-encoded chemical selections performed using DNA in single-stranded or double-stranded format.
Biochem Biophys Res Commun
; 533(2): 223-229, 2020 12 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-32386812
7.
Impact of Ligand Size and Conjugation Chemistry on the Performance of Universal Chimeric Antigen Receptor T-Cells for Tumor Killing.
Bioconjug Chem
; 31(7): 1775-1783, 2020 07 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32515934
8.
Response to: GCP III is not the "off-target" for urea-based PSMA-ligands.
Eur J Nucl Med Mol Imaging
; 50(10): 2947-2949, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37341746
9.
Discovery of Glutamate Carboxypeptidase III Ligands to Compete the Uptake of [177Lu]Lu-PSMA-617 in Healthy Organs.
J Med Chem
; 67(10): 8247-8260, 2024 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-38716576
10.
DNA-encoded chemical libraries enable the discovery of potent PSMA-ligands with substantially reduced affinity towards the GCPIII anti-target.
Chem Sci
; 15(18): 6789-6799, 2024 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38725500
11.
Impact of library input on the hit discovery rate in DNA-encoded chemical library selections.
Chem Sci
; 14(43): 12026-12033, 2023 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37969600
12.
Deep Learning Approach for the Discovery of Tumor-Targeting Small Organic Ligands from DNA-Encoded Chemical Libraries.
ACS Omega
; 8(28): 25090-25100, 2023 Jul 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-37483198
13.
A DNA-encoded chemical library based on chiral 4-amino-proline enables stereospecific isozyme-selective protein recognition.
Nat Chem
; 15(10): 1431-1443, 2023 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-37400597
14.
Isolation of a Natural Killer Group 2D Small-Molecule Ligand from DNA-Encoded Chemical Libraries.
ChemMedChem
; 17(21): e202200350, 2022 Nov 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-35929380
15.
Generation and in vivo validation of an IL-12 fusion protein based on a novel anti-human FAP monoclonal antibody.
J Immunother Cancer
; 10(9)2022 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-36104101
16.
Specific Inhibitor of Placental Alkaline Phosphatase Isolated from a DNA-Encoded Chemical Library Targets Tumor of the Female Reproductive Tract.
J Med Chem
; 64(21): 15799-15809, 2021 11 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34709820
17.
Stereo- and regiodefined DNA-encoded chemical libraries enable efficient tumour-targeting applications.
Nat Chem
; 13(6): 540-548, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33833446
18.
A Single-Stranded DNA-Encoded Chemical Library Based on a Stereoisomeric Scaffold Enables Ligand Discovery by Modular Assembly of Building Blocks.
Adv Sci (Weinh)
; 7(22): 2001970, 2020 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-33240760
19.
Screening of copper and palladium-mediated reactions compatible with DNA-encoded chemical libraries.
Helv Chim Acta
; 102(4)2019 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32292208
20.
DNA-encoded chemical libraries - achievements and remaining challenges.
FEBS Lett
; 592(12): 2168-2180, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29683493