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1.
Safety, tolerability, pharmacokinetics and pharmacodynamics of the anti-CD38 cytolytic antibody TAK-079 in healthy subjects.
Br J Clin Pharmacol
; 86(7): 1314-1325, 2020 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32045493
2.
A Reduction in B, T, and Natural Killer Cells Expressing CD38 by TAK-079 Inhibits the Induction and Progression of Collagen-Induced Arthritis in Cynomolgus Monkeys.
J Pharmacol Exp Ther
; 370(2): 182-196, 2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31085699
3.
Antagonizing the α4ß1 integrin, but not α4ß7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis.
J Immunol
; 190(5): 1961-73, 2013 Mar 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-23365083
4.
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single-Dose and Multiple-Rising-Dose Study of the BTK Inhibitor TAK-020 in Healthy Subjects.
Clin Transl Sci
; 14(3): 820-828, 2021 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33650758
5.
The binding specificity and selective antagonism of vedolizumab, an anti-alpha4beta7 integrin therapeutic antibody in development for inflammatory bowel diseases.
J Pharmacol Exp Ther
; 330(3): 864-75, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19509315
6.
Effect of an experimental proteasome inhibitor on the cytoskeleton, cytosolic protein turnover, and induction in the neuronal cells in vitro.
Neurotoxicology
; 29(2): 232-43, 2008 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-18155769
7.
Pharmacokinetics and pharmacodynamics of the cytolytic anti-CD38 human monoclonal antibody TAK-079 in monkey - model assisted preparation for the first in human trial.
Pharmacol Res Perspect
; 6(3): e00402, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29864242
8.
Pharmacological characterization of guinea pig chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2).
Prostaglandins Other Lipid Mediat
; 76(1-4): 133-47, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15967168
9.
Exclusive antagonism of the α4 ß7 integrin by vedolizumab confirms the gut-selectivity of this pathway in primates.
Inflamm Bowel Dis
; 18(11): 2107-19, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22419649
10.
Correlation of serpin-protease expression by comparative analysis of real-time PCR profiling data.
Genomics
; 88(2): 173-84, 2006 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-16713170
11.
Role of regulator of G protein signaling 16 in inflammation-induced T lymphocyte migration and activation.
J Immunol
; 171(3): 1542-55, 2003 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-12874248
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