Detalles de la búsqueda
1.
Fragment-based discovery of DNA gyrase inhibitors targeting the ATPase subunit of GyrB.
Bioorg Med Chem Lett
; 26(4): 1314-8, 2016 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26786695
2.
Comparing niraparib versus platinum-taxane doublet chemotherapy as neoadjuvant treatment in patients with newly diagnosed homologous recombination-deficient stage III/IV ovarian cancer: study protocol for cohort C of the open-label, phase 2, randomized controlled multicenter OPAL trial.
Trials
; 25(1): 301, 2024 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-38702828
3.
Niraparib, Dostarlimab, and Bevacizumab as Combination Therapy in Pretreated, Advanced Platinum-Resistant Ovarian Cancer: Findings From Cohort A of the OPAL Phase II Trial.
JCO Precis Oncol
; 8: e2300693, 2024 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-38754056
4.
The structure of mammalian serine racemase: evidence for conformational changes upon inhibitor binding.
J Biol Chem
; 285(17): 12873-81, 2010 Apr 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-20106978
5.
Ceralasertib-Mediated ATR Inhibition Combined With Olaparib in Advanced Cancers Harboring DNA Damage Response and Repair Alterations (Olaparib Combinations).
JCO Precis Oncol
; 52021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34527850
6.
Ceralasertib (AZD6738), an Oral ATR Kinase Inhibitor, in Combination with Carboplatin in Patients with Advanced Solid Tumors: A Phase I Study.
Clin Cancer Res
; 27(19): 5213-5224, 2021 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34301752
7.
Cross-linking of protein crystals as an aid in the generation of binary protein-ligand crystal complexes, exemplified by the human PDE10a-papaverine structure.
Acta Crystallogr D Biol Crystallogr
; 65(Pt 8): 872-4, 2009 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-19622871
8.
HCV NS5B polymerase inhibitors 2: Synthesis and in vitro activity of (1,1-dioxo-2H-[1,2,4]benzothiadiazin-3-yl) azolo[1,5-a]pyridine and azolo[1,5-a]pyrimidine derivatives.
Bioorg Med Chem Lett
; 19(15): 4480-3, 2009 Aug 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19500983
9.
Discovery and structure-activity relationship of potent and selective covalent inhibitors of transglutaminase 2 for Huntington's disease.
J Med Chem
; 55(3): 1021-46, 2012 Feb 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-22224594
10.
High-resolution crystal structure of human Mapkap kinase 3 in complex with a high affinity ligand.
Protein Sci
; 19(1): 168-73, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19937655
11.
Aristolochene synthase: mechanistic analysis of active site residues by site-directed mutagenesis.
J Am Chem Soc
; 126(23): 7212-21, 2004 Jun 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-15186158
Resultados
1 -
11
de 11
1
Próxima >
>>