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1.
Design and synthesis of (E)-1,2-diphenylethene-based EZH2 inhibitors.
Bioorg Med Chem Lett
; 30(5): 126957, 2020 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31959420
2.
Design, synthesis and biological evaluation of a novel tubulin inhibitor SKLB0565 targeting the colchicine binding site.
Bioorg Chem
; 97: 103695, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32120073
3.
Design, synthesis and biological evaluation of 3,5-dimethylisoxazole and pyridone derivatives as BRD4 inhibitors.
Bioorg Med Chem Lett
; 29(19): 126577, 2019 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31421967
4.
Novel Amphiphilic PROTAC with Enhanced Pharmacokinetic Properties for ALK Protein Degradation.
J Med Chem
; 67(12): 9842-9856, 2024 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38839424
5.
Discovery of Novel Proteolysis-Targeting Chimera Molecules as Degraders of Programmed Cell Death-Ligand 1 for Breast Cancer Therapy.
J Med Chem
; 2024 Jun 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-38889052
6.
Discovery of the GSH responsive "Y-PROTACs" targeting ALK and CDK4/6 as a potential treatment for cancer.
Eur J Med Chem
; 248: 115082, 2023 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36628851
7.
A novel VEGFR inhibitor ZLF-095 with potent antitumor activity and low toxicity.
Heliyon
; 9(5): e15152, 2023 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-37251840
8.
Design, synthesis and biological evaluation of 7-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)-2,3-dihydro-1H-inden-1-one derivatives as potent FAK inhibitors for the treatment of ovarian cancer.
Eur J Med Chem
; 228: 113978, 2022 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34810020
9.
Design and Synthesis of Fibroblast Growth Factor Receptor (FGFR) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Cancer.
J Med Chem
; 65(24): 16541-16569, 2022 12 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-36449947
10.
Design, synthesis and biological evaluations of a series of Pyrido[1,2-a]pyrimidinone derivatives as novel selective FGFR inhibitors.
Eur J Med Chem
; 220: 113499, 2021 Aug 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33940465
11.
Differential Expression of Renin-Angiotensin System-related Components in Patients with Rheumatoid Arthritis and Osteoarthritis.
Am J Med Sci
; 359(1): 17-26, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31785770
12.
Novel Dual BET and PLK1 Inhibitor WNY0824 Exerts Potent Antitumor Effects in CRPC by Inhibiting Transcription Factor Function and Inducing Mitotic Abnormality.
Mol Cancer Ther
; 19(6): 1221-1231, 2020 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32220972
13.
Penfluridol: An antipsychotic agent suppresses lung cancer cell growth and metastasis by inducing G0/G1 arrest and apoptosis.
Biomed Pharmacother
; 121: 109598, 2020 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-31733572
14.
Repositioning antipsychotic fluphenazine hydrochloride for treating triple negative breast cancer with brain metastases and lung metastases.
Am J Cancer Res
; 9(3): 459-478, 2019.
Artículo
en Inglés
| MEDLINE | ID: mdl-30949404
15.
Novel selective TOPK inhibitor SKLB-C05 inhibits colorectal carcinoma growth and metastasis.
Cancer Lett
; 445: 11-23, 2019 03 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-30590102
16.
YLT-11, a novel PLK4 inhibitor, inhibits human breast cancer growth via inducing maladjusted centriole duplication and mitotic defect.
Cell Death Dis
; 9(11): 1066, 2018 10 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-30337519
17.
The antipsychotic agent trifluoperazine hydrochloride suppresses triple-negative breast cancer tumor growth and brain metastasis by inducing G0/G1 arrest and apoptosis.
Cell Death Dis
; 9(10): 1006, 2018 09 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-30258182
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