Detalles de la búsqueda
1.
Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies.
Proc Natl Acad Sci U S A
; 112(50): 15354-9, 2015 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26621728
2.
A Combination of Structural and Empirical Analyses Delineates the Key Contacts Mediating Stability and Affinity Increases in an Optimized Biotherapeutic Single-chain Fv (scFv).
J Biol Chem
; 291(3): 1267-76, 2016 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-26515064
3.
Fundamental characteristics of the immunoglobulin VH repertoire of chickens in comparison with those of humans, mice, and camelids.
J Immunol
; 188(1): 322-33, 2012 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22131336
4.
An ultra-specific avian antibody to phosphorylated tau protein reveals a unique mechanism for phosphoepitope recognition.
J Biol Chem
; 287(53): 44425-34, 2012 Dec 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-23148212
5.
Discovery and multi-parametric optimization of a high-affinity antibody against interleukin-25 with neutralizing activity in a mouse model of skin inflammation.
Antib Ther
; 5(4): 258-267, 2022 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-36299415
6.
Impacts of fast production of afucosylated antibodies and Fc mutants in ExpiCHO-S™ for enhancing FcγRIIIa binding and NK cell activation.
J Biotechnol
; 360: 79-91, 2022 Dec 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36341973
7.
A simple high-throughput purification method for hit identification in protein screening.
J Immunol Methods
; 339(1): 38-46, 2008 Nov 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-18760282
8.
Establishing in vitro in vivo correlations to screen monoclonal antibodies for physicochemical properties related to favorable human pharmacokinetics.
MAbs
; 10(2): 244-255, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-29271699
9.
Cellular and molecular actions of dinitroaniline and phosphorothioamidate herbicides on Plasmodium falciparum: tubulin as a specific antimalarial target.
Mol Biochem Parasitol
; 145(2): 226-38, 2006 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-16406111
10.
Antimitotic herbicides bind to an unidentified site on malarial parasite tubulin and block development of liver-stage Plasmodium parasites.
Mol Biochem Parasitol
; 188(2): 116-27, 2013 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-23523992
11.
Comprehensive interrogation of a minimalist synthetic CDR-H3 library and its ability to generate antibodies with therapeutic potential.
J Mol Biol
; 425(10): 1712-30, 2013 May 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-23429058
12.
CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery.
MAbs
; 5(6): 882-95, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23995618
13.
Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.
J Mol Biol
; 388(3): 541-58, 2009 May 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-19285987
Resultados
1 -
13
de 13
1
Próxima >
>>