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1.
Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFßR1 Inhibitor as an Immuno-oncology Agent.
ACS Med Chem Lett
; 11(2): 172-178, 2020 Feb 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-32071685
2.
Optimization of Nicotinamides as Potent and Selective IRAK4 Inhibitors with Efficacy in a Murine Model of Psoriasis.
ACS Med Chem Lett
; 11(7): 1402-1409, 2020 Jul 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32676146
3.
Miniaturized High-Throughput Multiparameter Flow Cytometry Assays Measuring In Vitro Human Dendritic Cell Maturation and T-Cell Activation in Mixed Lymphocyte Reactions.
SLAS Discov
; 23(7): 742-750, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29873570
4.
Discovery of 4-Azaindole Inhibitors of TGFßRI as Immuno-oncology Agents.
ACS Med Chem Lett
; 9(11): 1117-1122, 2018 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-30429955
5.
Development of a Human Whole Blood Screening Platform to Monitor JAK/STAT Signaling Using High-Throughput Flow Cytometry.
J Biomol Screen
; 21(8): 866-74, 2016 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-27142718
6.
Antroquinonol A: Scalable Synthesis and Preclinical Biology of a Phase 2 Drug Candidate.
ACS Cent Sci
; 2(1): 27-31, 2016 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-27163023
7.
Targeted disruption of ß-arrestin 2-mediated signaling pathways by aptamer chimeras leads to inhibition of leukemic cell growth.
PLoS One
; 9(4): e93441, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24736311
8.
The nuclear receptor coactivator amplified in breast cancer-1 is required for Neu (ErbB2/HER2) activation, signaling, and mammary tumorigenesis in mice.
Cancer Res
; 68(10): 3697-706, 2008 May 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-18483252
9.
Tyrosine phosphorylation of the nuclear receptor coactivator AIB1/SRC-3 is enhanced by Abl kinase and is required for its activity in cancer cells.
Mol Cell Biol
; 28(21): 6580-93, 2008 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-18765637
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