Detalles de la búsqueda
1.
Insights into E.â coli Cyclopropane Fatty Acid Synthase (CFAS) Towards Enantioselective Carbene Free Biocatalytic Cyclopropanation.
Angew Chem Int Ed Engl
; : e202403493, 2024 Apr 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-38662909
2.
Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C.
PLoS Biol
; 18(11): e3000904, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33156822
3.
A novel interaction between dengue virus nonstructural protein 1 and the NS4A-2K-4B precursor is required for viral RNA replication but not for formation of the membranous replication organelle.
PLoS Pathog
; 15(5): e1007736, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-31071189
4.
Concise synthesis and biological evaluation of 2-Aryl-3-Anilinobenzo[b]thiophene derivatives as potent apoptosis-inducing agents.
Bioorg Chem
; 112: 104919, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33957538
5.
Rational modifications, synthesis and biological evaluation of new potential antivirals for RSV designed to target the M2-1 protein.
Bioorg Med Chem
; 28(8): 115401, 2020 04 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32143992
6.
Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
Bioorg Chem
; 97: 103665, 2020 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-32086053
7.
Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins.
Molecules
; 25(21)2020 Oct 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-33114011
8.
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents.
Molecules
; 25(9)2020 May 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32384805
9.
Synthesis and Biological Evaluation of New Antitubulin Agents Containing 2-(3',4',5'-trimethoxyanilino)-3,6-disubstituted-4,5,6,7-tetrahydrothieno[2,3-c]pyridine Scaffold.
Molecules
; 25(7)2020 Apr 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-32272719
10.
Synthesis and biological evaluation of 6-substituted-5-fluorouridine ProTides.
Bioorg Med Chem
; 26(3): 551-565, 2018 02 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29277307
11.
3-Aryl/Heteroaryl-5-amino-1-(3',4',5'-trimethoxybenzoyl)-1,2,4-triazoles as antimicrotubule agents. Design, synthesis, antiproliferative activity and inhibition of tubulin polymerization.
Bioorg Chem
; 80: 361-374, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29986184
12.
Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication.
Bioorg Med Chem
; 25(1): 327-337, 2017 01 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27856239
13.
Rational design and synthesis of novel anti-prostate cancer agents bearing a 3,5-bis-trifluoromethylphenyl moiety.
Bioorg Med Chem Lett
; 26(15): 3636-40, 2016 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27301368
14.
Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71.
Eur J Med Chem
; 246: 114942, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36455356
15.
Handheld Raman Spectroscopy in the First UK Home Office Licensed Pharmacist-Led Community Drug Checking Service.
Int J Environ Res Public Health
; 20(6)2023 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36981705
16.
Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts.
ACS Catal
; 13(5): 3370-3378, 2023 Mar 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36910872
17.
A Composite System Based upon Hydroxypropyl Cyclodextrins and Soft Hydrogel Contact Lenses for the Delivery of Therapeutic Doses of Econazole to the Cornea, In Vitro.
Pharmaceutics
; 14(8)2022 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36015257
18.
Synthesis and Biological Evaluation of Highly Active 7-Anilino Triazolopyrimidines as Potent Antimicrotubule Agents.
Pharmaceutics
; 14(6)2022 Jun 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-35745764
19.
Design, Synthesis and Biological Investigation of 2-Anilino Triazolopyrimidines as Tubulin Polymerization Inhibitors with Anticancer Activities.
Pharmaceuticals (Basel)
; 15(8)2022 Aug 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-36015179
20.
Structural Investigations on Novel Non-Nucleoside Inhibitors of Human Norovirus Polymerase.
Viruses
; 15(1)2022 12 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-36680114