Detalles de la búsqueda
1.
Analysis of the Clinical Pipeline of Treatments for Drug-Resistant Bacterial Infections: Despite Progress, More Action Is Needed.
Antimicrob Agents Chemother
; 66(3): e0199121, 2022 03 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-35007139
2.
Pharmacokinetic/Pharmacodynamic Evaluation of Solithromycin against Streptococcus pneumoniae Using Data from a Neutropenic Murine Lung Infection Model.
Antimicrob Agents Chemother
; 63(8)2019 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-31182534
3.
Analyzing the Mechanisms Behind Macrolide Antibiotic-Induced Liver Injury Using Quantitative Systems Toxicology Modeling.
Pharm Res
; 36(3): 48, 2019 Feb 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30734107
4.
Activities of Combinations of Antistaphylococcal Antibiotics with Fusidic Acid against Staphylococcal Biofilms in In Vitro Static and Dynamic Models.
Antimicrob Agents Chemother
; 62(7)2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29712650
5.
Metabolism, Excretion, and Mass Balance of Solithromycin in Humans.
Antimicrob Agents Chemother
; 62(5)2018 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-29507061
6.
Reply to Kaye and Belley, "Third-Generation Cephalosporin-Resistant Enterobacterales Are Critical Priority Pathogens, Too!"
Antimicrob Agents Chemother
; 66(4): e0022322, 2022 04 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-35323014
7.
Solithromycin, a novel macrolide, does not prolong cardiac repolarization: a randomized, three-way crossover study in healthy subjects.
J Antimicrob Chemother
; 72(2): 515-521, 2017 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-27798210
8.
SOLITAIRE-IV: A Randomized, Double-Blind, Multicenter Study Comparing the Efficacy and Safety of Intravenous-to-Oral Solithromycin to Intravenous-to-Oral Moxifloxacin for Treatment of Community-Acquired Bacterial Pneumonia.
Clin Infect Dis
; 63(8): 1007-1016, 2016 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27448679
9.
In Vitro Activity of Solithromycin against Bordetella pertussis, an Emerging Respiratory Pathogen.
Antimicrob Agents Chemother
; 60(12): 7043-7045, 2016 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-27620481
10.
Solithromycin Pharmacokinetics in Plasma and Dried Blood Spots and Safety in Adolescents.
Antimicrob Agents Chemother
; 60(4): 2572-6, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26883693
11.
The solithromycin journey-It is all in the chemistry.
Bioorg Med Chem
; 24(24): 6420-6428, 2016 12 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27595539
12.
A Phase 2 Trial of Oral Solithromycin 1200 mg or 1000 mg as Single-Dose Oral Therapy for Uncomplicated Gonorrhea.
Clin Infect Dis
; 61(7): 1043-8, 2015 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26089222
13.
Safety and Pharmacokinetics of Solithromycin in Subjects with Hepatic Impairment.
Antimicrob Agents Chemother
; 59(8): 4379-86, 2015 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-25870056
14.
Antimicrobial activity of solithromycin against clinical isolates of Legionella pneumophila serogroup 1.
Antimicrob Agents Chemother
; 58(2): 909-15, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24277019
15.
In vitro activity of the new fluoroketolide solithromycin (CEM-101) against macrolide-resistant and -susceptible Mycoplasma genitalium strains.
Antimicrob Agents Chemother
; 58(6): 3151-6, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24637681
16.
In vitro activity of solithromycin against erythromycin-resistant Streptococcus agalactiae.
Antimicrob Agents Chemother
; 58(3): 1693-8, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24379197
17.
Maternal administration of solithromycin, a new, potent, broad-spectrum fluoroketolide antibiotic, achieves fetal and intra-amniotic antimicrobial protection in a pregnant sheep model.
Antimicrob Agents Chemother
; 58(1): 447-54, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24189250
18.
Determination of In Vitro Activities of Solithromycin at Different pHs and Its Intracellular Activity against Clinical Isolates of Neisseria gonorrhoeae from a Laboratory Collection.
Antimicrob Agents Chemother
; 57(9): 4322-4328, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23796936
19.
Erratum for Piccinelli et al., "In Vitro Activity of Solithromycin against Erythromycin-Resistant Streptococcus agalactiae".
Antimicrob Agents Chemother
; 62(11)2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30355751
20.
Randomized, double-blind, multicenter phase 2 study comparing the efficacy and safety of oral solithromycin (CEM-101) to those of oral levofloxacin in the treatment of patients with community-acquired bacterial pneumonia.
Antimicrob Agents Chemother
; 57(6): 2526-34, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23507282