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1.
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 3. Structure-activity studies of ketomethylene-containing peptidomimetics.
J Med Chem
; 42(7): 1203-12, 1999 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-10197964
2.
Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease.
J Med Chem
; 39(26): 5072-82, 1996 Dec 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-8978838
3.
Substituted benzamide inhibitors of human rhinovirus 3C protease: structure-based design, synthesis, and biological evaluation.
J Med Chem
; 43(9): 1670-83, 2000 May 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-10794684
4.
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 4. Incorporation of P1 lactam moieties as L-glutamine replacements.
J Med Chem
; 42(7): 1213-24, 1999 Apr 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-10197965
5.
Tripeptide aldehyde inhibitors of human rhinovirus 3C protease: design, synthesis, biological evaluation, and cocrystal structure solution of P1 glutamine isosteric replacements.
J Med Chem
; 41(15): 2786-805, 1998 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-9667969
6.
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 1. Michael acceptor structure-activity studies.
J Med Chem
; 41(15): 2806-18, 1998 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-9667970
7.
Structure-based design, synthesis, and biological evaluation of irreversible human rhinovirus 3C protease inhibitors. 2. Peptide structure-activity studies.
J Med Chem
; 41(15): 2819-34, 1998 Jul 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-9667971
8.
2.3 A crystal structure of the catalytic domain of DNA polymerase beta.
Cell
; 76(6): 1123-33, 1994 Mar 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-8137427
9.
Structure of human rhinovirus 3C protease reveals a trypsin-like polypeptide fold, RNA-binding site, and means for cleaving precursor polyprotein.
Cell
; 77(5): 761-71, 1994 Jun 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-7515772
10.
Structure-based design of ketone-containing, tripeptidyl human rhinovirus 3C protease inhibitors.
Bioorg Med Chem Lett
; 10(1): 45-8, 2000 Jan 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-10636240
11.
Structure-based design of irreversible, tripeptidyl human rhinovirus 3C protease inhibitors containing N-methyl amino acids.
Bioorg Med Chem Lett
; 9(15): 2189-94, 1999 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-10465543
12.
Design and synthesis of irreversible depsipeptidyl human rhinovirus 3C protease inhibitors.
Bioorg Med Chem Lett
; 11(20): 2683-6, 2001 Oct 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-11591501
13.
Structure-assisted design of mechanism-based irreversible inhibitors of human rhinovirus 3C protease with potent antiviral activity against multiple rhinovirus serotypes.
Proc Natl Acad Sci U S A
; 96(20): 11000-7, 1999 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-10500114
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