Detalles de la búsqueda
1.
Repurposing ibudilast to mitigate Alzheimer's disease by targeting inflammation.
Brain
; 146(3): 898-911, 2023 03 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-35411386
2.
Prostaglandin D2/J2 signaling pathway in a rat model of neuroinflammation displaying progressive parkinsonian-like pathology: potential novel therapeutic targets.
J Neuroinflammation
; 15(1): 272, 2018 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-30236122
3.
Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease.
Biochim Biophys Acta Mol Basis Dis
; 1863(6): 1157-1170, 2017 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-28372990
4.
PACAP27 prevents Parkinson-like neuronal loss and motor deficits but not microglia activation induced by prostaglandin J2.
Biochim Biophys Acta
; 1842(9): 1707-19, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24970746
5.
Negative regulation of 26S proteasome stability via calpain-mediated cleavage of Rpn10 subunit upon mitochondrial dysfunction in neurons.
J Biol Chem
; 288(17): 12161-74, 2013 Apr 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-23508964
6.
Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.
J Biol Chem
; 286(25): 22426-40, 2011 Jun 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-21536669
7.
Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implications.
Apoptosis
; 15(11): 1292-311, 2010 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-20131003
8.
PACAP27 mitigates an age-dependent hippocampal vulnerability to PGJ2-induced spatial learning deficits and neuroinflammation in mice.
Brain Behav
; 10(1): e01465, 2020 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31769222
9.
Proteasome-caspase-cathepsin sequence leading to tau pathology induced by prostaglandin J2 in neuronal cells.
J Neurochem
; 110(1): 328-42, 2009 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-19457109
10.
Subchronic infusion of the product of inflammation prostaglandin J2 models sporadic Parkinson's disease in mice.
J Neuroinflammation
; 6: 18, 2009 Jul 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-19630993
11.
Mitochondrial and calcium perturbations in rat CNS neurons induce calpain-cleavage of Parkin: Phosphatase inhibition stabilizes pSer65Parkin reducing its calpain-cleavage.
Biochim Biophys Acta Mol Basis Dis
; 1865(6): 1436-1450, 2019 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30796971
12.
Aging and regulated protein degradation: who has the UPPer hand?
Aging Cell
; 6(5): 599-606, 2007 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-17681036
13.
Aging perturbs 26S proteasome assembly in Drosophila melanogaster.
FASEB J
; 21(11): 2672-82, 2007 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-17413001
14.
Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and ß-secretases: relevance to Alzheimer's disease.
Neurobiol Aging
; 62: 130-145, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29149631
15.
Chronic voluntary oral methamphetamine induces deficits in spatial learning and hippocampal protein kinase Mzeta with enhanced astrogliosis and cyclooxygenase-2 levels.
Heliyon
; 4(2): e00509, 2018 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-29560440
16.
Prostaglandin J2: a potential target for halting inflammation-induced neurodegeneration.
Ann N Y Acad Sci
; 1363: 125-37, 2016 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-26748744
17.
The Ubiquitin-Proteasome System: Potential Therapeutic Targets for Alzheimer's Disease and Spinal Cord Injury.
Front Mol Neurosci
; 9: 4, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-26858599
18.
Neurodegeneration: linking ubiquitin/proteasome pathway impairment with inflammation.
Int J Biochem Cell Biol
; 35(5): 547-52, 2003 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-12672447
19.
Neuroinflammation and J2 prostaglandins: linking impairment of the ubiquitin-proteasome pathway and mitochondria to neurodegeneration.
Front Mol Neurosci
; 7: 104, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25628533
20.
Regulating the ubiquitin/proteasome pathway via cAMP-signaling: neuroprotective potential.
Cell Biochem Biophys
; 67(1): 55-66, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23686612