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1.
Fragment-based drug discovery applied to Hsp90. Discovery of two lead series with high ligand efficiency.
J Med Chem
; 53(16): 5942-55, 2010 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-20718493
2.
Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design.
J Med Chem
; 53(16): 5956-69, 2010 Aug 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-20662534
3.
Preparation of kinase-biased compounds in the search for lead inhibitors of kinase targets.
Med Res Rev
; 25(3): 310-30, 2005 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-15593285
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