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1.
Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR.
J Biol Chem
; 300(5): 107251, 2024 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38569939
2.
Constitutive Activation of gp130 in T Cells Results in Senescence and Premature Aging.
J Immunol
; 210(11): 1641-1652, 2023 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37058108
3.
Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95.
J Biol Chem
; 299(8): 104989, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37392849
4.
Bispecific soluble cytokine receptor-nanobody fusions inhibit Interleukin (IL-)6 trans-signaling and IL-12/23 or tumor necrosis factor (TNF) signaling.
J Biol Chem
; 299(11): 105343, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37838173
5.
Respiratory syncytial virus-approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors.
J Biol Chem
; 299(11): 105270, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37734558
6.
Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rß1 and subsequent signal transduction.
J Biol Chem
; 297(5): 101295, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34637790
7.
Immunoreceptor Engineering and Synthetic Cytokine Signaling for Therapeutics.
Trends Immunol
; 40(3): 258-272, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30738638
8.
Synthetic interleukin 22 (IL-22) signaling reveals biological activity of homodimeric IL-10 receptor 2 and functional cross-talk with the IL-6 receptor gp130.
J Biol Chem
; 295(35): 12378-12397, 2020 08 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-32611765
9.
Deciphering site 3 interactions of interleukin 12 and interleukin 23 with their cognate murine and human receptors.
J Biol Chem
; 295(30): 10478-10492, 2020 07 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-32518162
10.
Current status and relevance of single nucleotide polymorphisms in IL-6-/IL-12-type cytokine receptors.
Cytokine
; 148: 155550, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34217594
11.
IL-6 Trans-signaling Controls Liver Regeneration After Partial Hepatectomy.
Hepatology
; 70(6): 2075-2091, 2019 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-31100194
12.
Combined deletion of the fibronectin-type III domains and the stalk region results in ligand-independent, constitutive activation of the Interleukin 6 signal-transducing receptor gp130.
Cytokine
; 110: 428-434, 2018 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29789201
13.
CD73-derived adenosine and tenascin-C control cytokine production by epicardium-derived cells formed after myocardial infarction.
FASEB J
; 31(7): 3040-3053, 2017 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-28363952
14.
Human and Murine Interleukin 23 Receptors Are Novel Substrates for A Disintegrin and Metalloproteases ADAM10 and ADAM17.
J Biol Chem
; 291(20): 10551-61, 2016 May 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-26961870
15.
Non-canonical interleukin 23 receptor complex assembly: p40 protein recruits interleukin 12 receptor ß1 via site II and induces p19/interleukin 23 receptor interaction via site III.
J Biol Chem
; 290(1): 359-70, 2015 Jan 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-25371211
16.
The amino acid exchange R28E in ciliary neurotrophic factor (CNTF) abrogates interleukin-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130 (gp130)/leukemia inhibitory factor receptor (LIFR).
J Biol Chem
; 289(26): 18442-50, 2014 Jun 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24802752
17.
Alternative intronic polyadenylation generates the interleukin-6 trans-signaling inhibitor sgp130-E10.
J Biol Chem
; 289(32): 22140-50, 2014 Aug 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-24973212
18.
Identification of canonical tyrosine-dependent and non-canonical tyrosine-independent STAT3 activation sites in the intracellular domain of the interleukin 23 receptor.
J Biol Chem
; 288(27): 19386-400, 2013 Jul 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-23673666
19.
Constitutively active mutant gp130 receptor protein from inflammatory hepatocellular adenoma is inhibited by an anti-gp130 antibody that specifically neutralizes interleukin 11 signaling.
J Biol Chem
; 287(17): 13743-51, 2012 Apr 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-22523320
20.
ELPylated haemagglutinins produced in tobacco plants induce potentially neutralizing antibodies against H5N1 viruses in mice.
Plant Biotechnol J
; 11(5): 582-93, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23398695