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1.
Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.
Aging Cell
; 17(4): e12769, 2018 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-29696791
2.
Down-regulation of the mitochondrial matrix peptidase ClpP in muscle cells causes mitochondrial dysfunction and decreases cell proliferation.
Free Radic Biol Med
; 91: 281-92, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26721594
3.
Gene expression in the liver of female, but not male mice treated with rapamycin resembles changes observed under dietary restriction.
Springerplus
; 4: 174, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-26034704
4.
Rapamycin and dietary restriction induce metabolically distinctive changes in mouse liver.
J Gerontol A Biol Sci Med Sci
; 70(4): 410-20, 2015 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24755936
5.
Short-term rapamycin treatment in mice has few effects on the transcriptome of white adipose tissue compared to dietary restriction.
Mech Ageing Dev
; 140: 23-9, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-25075714
6.
Combined treatment of rapamycin and dietary restriction has a larger effect on the transcriptome and metabolome of liver.
Aging Cell
; 13(2): 311-9, 2014 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-24304444
7.
Mice fed rapamycin have an increase in lifespan associated with major changes in the liver transcriptome.
PLoS One
; 9(1): e83988, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24409289
8.
Short-term treatment with rapamycin and dietary restriction have overlapping and distinctive effects in young mice.
J Gerontol A Biol Sci Med Sci
; 68(2): 108-16, 2013 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-22570137
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