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1.
A Phase 1 Dose-Escalation Study of PF-06671008, a Bispecific T-Cell-Engaging Therapy Targeting P-Cadherin in Patients With Advanced Solid Tumors.
Front Immunol
; 13: 845417, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35493516
2.
First-in-human study of an OX40 (ivuxolimab) and 4-1BB (utomilumab) agonistic antibody combination in patients with advanced solid tumors.
J Immunother Cancer
; 10(10)2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36302562
3.
Association of Tumor Mutational Burden and Immune Gene Expression with Response to PD-1 Blockade by Sasanlimab Across Tumor Types and Routes of Administration.
Target Oncol
; 16(6): 773-787, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34694529
4.
Assessment of Subcutaneous vs Intravenous Administration of Anti-PD-1 Antibody PF-06801591 in Patients With Advanced Solid Tumors: A Phase 1 Dose-Escalation Trial.
JAMA Oncol
; 5(7): 999-1007, 2019 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-31145415
5.
Single and multiple ascending-dose study of glucagon-receptor antagonist RN909 in type 2 diabetes: a phase 1, randomized, double-blind, placebo-controlled trial.
Endocrine
; 62(2): 371-380, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30203123
6.
Generation of a high-fidelity antibody against nerve growth factor using library scanning mutagenesis and validation with structures of the initial and optimized Fab-antigen complexes.
MAbs
; 6(4): 1059-68, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24830649
7.
TrkB and TrkC agonist antibodies improve function, electrophysiologic and pathologic features in Trembler J mice.
Exp Neurol
; 224(2): 495-506, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20553714
8.
Proneurotrophins require endocytosis and intracellular proteolysis to induce TrkA activation.
J Biol Chem
; 283(19): 12709-16, 2008 May 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-18299325
9.
Appetite enhancement and weight gain by peripheral administration of TrkB agonists in non-human primates.
PLoS One
; 3(4): e1900, 2008 Apr 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-18382675
10.
Treatment with trkC agonist antibodies delays disease progression in neuromuscular degeneration (nmd) mice.
Hum Mol Genet
; 14(13): 1825-37, 2005 Jul 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-15888478
11.
Macrophage stimulating protein is a target-derived neurotrophic factor for developing sensory and sympathetic neurons.
Development
; 130(5): 995-1002, 2003 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-12538524
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