Detalles de la búsqueda
1.
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability.
Pharmacogenet Genomics
; 34(4): 91-104, 2024 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-38682317
2.
LDLR and PCSK9 3´UTR variants and their putative effects on microRNA molecular interactions in familial hypercholesterolemia: a computational approach.
Mol Biol Rep
; 50(11): 9165-9177, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37776414
3.
Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia.
Chem Phys Lipids
; 257: 105348, 2023 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-37827478
4.
LDLR missense variants disturb structural conformation and LDLR activity in T-lymphocytes of Familial hypercholesterolemia patients.
Gene
; 853: 147084, 2023 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36464169
5.
Effects of PCSK9 missense variants on molecular conformation and biological activity in transfected HEK293FT cells.
Gene
; 851: 146979, 2023 Jan 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-36261084
6.
In silico analysis of upstream variants in Brazilian patients with Familial hypercholesterolemia.
Gene
; 849: 146908, 2023 Jan 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-36167182
7.
Identification of pathogenic variants in the Brazilian cohort with Familial hypercholesterolemia using exon-targeted gene sequencing.
Gene
; 875: 147501, 2023 Jul 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-37217153
8.
Genetic Variant ABCC1 rs45511401 Is Associated with Increased Response to Statins in Patients with Familial Hypercholesterolemia.
Pharmaceutics
; 14(5)2022 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35631530
9.
Circulating Extracellular Vesicles As Biomarkers and Drug Delivery Vehicles in Cardiovascular Diseases.
Biomolecules
; 11(3)2021 03 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33808038
10.
Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report.
Ann Transl Med
; 9(1): 76, 2021 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-33553369
11.
Genomics, epigenomics and pharmacogenomics of familial hypercholesterolemia (FHBGEP): A study protocol.
Res Social Adm Pharm
; 17(7): 1347-1355, 2021 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33129683
12.
Differentially expressed urinary exo-miRs and clinical outcomes in kidney recipients on short-term tacrolimus therapy: a pilot study.
Epigenomics
; 12(22): 2019-2034, 2020 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-33275448
13.
The impact of vitamin D supplementation on VDR gene expression and body composition in monozygotic twins: randomized controlled trial.
Sci Rep
; 10(1): 11943, 2020 07 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-32686744
14.
Predicted deleterious variants in ABCA1, LPL, LPA and KIF6 are associated with statin response and adverse events in patients with familial hypercholesterolemia and disturb protein structure and stability
Pharmacogenet. genomics
; 34(4): 91-104, jun.2024.
Artículo
en Inglés
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1552919
15.
Lipidomic analysis identified potential predictive biomarkers of statin response in subjects with Familial hypercholesterolemia
Chem. Phys. lipids
; 257: 105348, nov.2023. ilus
Artículo
en Inglés
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1524856
16.
LDLR and PCSK9 3´UTR variants and their putative effects on microRNA molecular interactions in familial hypercholesterolemia: a computational approach
Mol. Biol. reports
; 50: 9165-9177, set.2023. ilus
Artículo
en Inglés
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1525357
17.
Circulating MicroRNAs as Potential Biomarkers of Atrial Fibrillation.
Biomed Res Int
; 2017: 7804763, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28349066
18.
Genetic variant ABCC1 rs45511401 is associated with increased response to statins in patients with familial hypercholesterolemia
Pharmaceutics
; 14(5): 1-20, Apr.2022. tab, ilus, graf
Artículo
en Inglés
| CONASS, SES-SP, SESSP-IDPCPROD, SES-SP | ID: biblio-1371140
19.
Integrated analysis of miRNA and mRNA gene expression microarrays: Influence on platelet reactivity, clopidogrel response and drug-induced toxicity.
Gene
; 593(1): 172-178, 2016 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27543010
20.
Late response to rosuvastatin and statin-related myalgia due to SLCO1B1, SLCO1B3, ABCB11, and CYP3A5 variants in a patient with Familial Hypercholesterolemia: a case report
Ann. transl. med. (Online)
; 9(1): 1-8, Jan. 2021. graf, tab, ilus
Artículo
en Inglés
| SES-SP, CONASS, SESSP-IDPCPROD, SES-SP | ID: biblio-1147556