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1.
Gigaxonin Suppresses Epithelial-to-Mesenchymal Transition of Human Cancer Through Downregulation of Snail.
Cancer Res Commun
; 4(3): 706-722, 2024 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-38421310
2.
The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance.
J Biol Chem
; 287(26): 21796-805, 2012 Jun 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-22556409
3.
Dietary ß-glucan stimulate complement and C-reactive protein acute phase responses in common carp (Cyprinus carpio) during an Aeromonas salmonicida infection.
Fish Shellfish Immunol
; 34(3): 819-31, 2013 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-23291104
4.
Acidification of intracellular pH in MM tumor cells overcomes resistance to hypoxia-mediated apoptosis in vitro and in vivo.
Front Oncol
; 13: 1268421, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-38023253
5.
IL-6-induced enhancement of c-Myc translation in multiple myeloma cells: critical role of cytoplasmic localization of the rna-binding protein hnRNP A1.
J Biol Chem
; 286(1): 67-78, 2011 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-20974848
6.
Targeting TORC2 in multiple myeloma with a new mTOR kinase inhibitor.
Blood
; 116(22): 4560-8, 2010 Nov 25.
Artículo
en Inglés
| MEDLINE | ID: mdl-20686120
7.
Reduced inflammatory response to Aeromonas salmonicida infection in common carp (Cyprinus carpio L.) fed with ß-glucan supplements.
Fish Shellfish Immunol
; 32(6): 1051-7, 2012 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-22406448
8.
Molecular cloning and expression of two ß-defensin and two mucin genes in common carp (Cyprinus carpio L.) and their up-regulation after ß-glucan feeding.
Fish Shellfish Immunol
; 32(3): 494-501, 2012 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-22227003
9.
Can Targeting Hypoxia-Mediated Acidification of the Bone Marrow Microenvironment Kill Myeloma Tumor Cells?
Front Oncol
; 11: 703878, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-34350119
10.
AcidoCEST MRI Evaluates the Bone Microenvironment in Multiple Myeloma.
Mol Imaging Biol
; 23(6): 865-873, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-33939066
11.
Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin.
Mol Cancer Ther
; 8(1): 83-93, 2009 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19139116
12.
Multimodal Bioluminescent and Positronic-emission Tomography/Computational Tomography Imaging of Multiple Myeloma Bone Marrow Xenografts in NOG Mice.
J Vis Exp
; (143)2019 01 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30663654
13.
A Novel Therapeutic Induces DEPTOR Degradation in Multiple Myeloma Cells with Resulting Tumor Cytotoxicity.
Mol Cancer Ther
; 18(10): 1822-1831, 2019 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-31395691
14.
Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis.
Cancer Res
; 66(4): 2305-13, 2006 Feb 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-16489035
15.
Restoration of the prolyl-hydroxylase domain protein-3 oxygen-sensing mechanism is responsible for regulation of HIF2α expression and induction of sensitivity of myeloma cells to hypoxia-mediated apoptosis.
PLoS One
; 12(12): e0188438, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-29206844
16.
Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade.
Mol Cancer Ther
; 4(10): 1533-40, 2005 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-16227402
17.
A DNA-binding Molecule Targeting the Adaptive Hypoxic Response in Multiple Myeloma Has Potent Antitumor Activity.
Mol Cancer Res
; 14(3): 253-66, 2016 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-26801054
18.
SGK Kinase Activity in Multiple Myeloma Cells Protects against ER Stress Apoptosis via a SEK-Dependent Mechanism.
Mol Cancer Res
; 14(4): 397-407, 2016 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-26869290
19.
Cytotoxic Properties of a DEPTOR-mTOR Inhibitor in Multiple Myeloma Cells.
Cancer Res
; 76(19): 5822-5831, 2016 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-27530328
20.
Interleukin-6 activates phosphoinositol-3' kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways.
Oncogene
; 23(19): 3368-75, 2004 Apr 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-15021914