Detalles de la búsqueda
1.
Discovery of dual tubulin-NEDDylation inhibitors with antiproliferative activity.
J Enzyme Inhib Med Chem
; 38(1): 166-175, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-36330714
2.
Discovery of novel indole derivatives that inhibit NEDDylation and MAPK pathways against gastric cancer MGC803 cells.
Bioorg Chem
; 107: 104634, 2021 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-33476867
3.
Ras/Raf/MEK/ERK pathway axis mediated neurotoxicity induced by high-risk pesticide residue-Avermectin.
Environ Toxicol
; 36(5): 984-993, 2021 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-33381906
4.
Gartanin is a novel NEDDylation inhibitor for induction of Skp2 degradation, FBXW2 expression, and autophagy.
Mol Carcinog
; 59(2): 193-201, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31782573
5.
Novel piperidine derivatives as colchicine binding site inhibitors induce apoptosis and inhibit epithelial-mesenchymal transition against prostate cancer PC3 cells.
J Enzyme Inhib Med Chem
; 35(1): 1403-1413, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32588683
6.
Antiproliferative benzothiazoles incorporating a trimethoxyphenyl scaffold as novel colchicine site tubulin polymerisation inhibitors.
J Enzyme Inhib Med Chem
; 35(1): 1050-1059, 2020 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-32299262
7.
Discovery of novel chalcone-dithiocarbamates as ROS-mediated apoptosis inducers by inhibiting catalase.
Bioorg Chem
; 86: 375-385, 2019 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30763884
8.
Identification of osimertinib (AZD9291) as a lysine specific demethylase 1 inhibitor.
Bioorg Chem
; 84: 164-169, 2019 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30502627
9.
Discovery of indoline derivatives that inhibit esophageal squamous cell carcinoma growth by Noxa mediated apoptosis.
Bioorg Chem
; 92: 103190, 2019 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-31465969
10.
Molecular diversity of phenothiazines: design and synthesis of phenothiazine-dithiocarbamate hybrids as potential cell cycle blockers.
Mol Divers
; 21(4): 933-942, 2017 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-28785928
11.
Design and Antiproliferative Evaluation of Novel Sulfanilamide Derivatives as Potential Tubulin Polymerization Inhibitors.
Molecules
; 22(9)2017 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-28872607
12.
Design, synthesis and antiproliferative activity studies of novel dithiocarbamate-chalcone derivates.
Bioorg Med Chem Lett
; 26(16): 3918-22, 2016 08 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-27423479
13.
Design, Synthesis and Structure-Activity Relationships of Novel Chalcone-1,2,3-triazole-azole Derivates as Antiproliferative Agents.
Molecules
; 21(5)2016 May 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-27213317
14.
Targeting NEDD8-activating enzyme for cancer therapy: developments, clinical trials, challenges and future research directions.
J Hematol Oncol
; 16(1): 87, 2023 07 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-37525282
15.
Synthesis of S-2-phenylchromane Derivatives and Evaluation of the Antiproliferative Properties as Apoptosis Inducers in Cancer Cell Lines.
Anticancer Agents Med Chem
; 23(16): 1848-1859, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37139673
16.
Annual review of LSD1/KDM1A inhibitors in 2020.
Eur J Med Chem
; 214: 113254, 2021 Mar 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-33581557
17.
ß-Lactams as promising anticancer agents: Molecular hybrids, structure activity relationships and potential targets.
Eur J Med Chem
; 201: 112510, 2020 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32592915
18.
Discovery of novel tertiary amide derivatives as NEDDylation pathway activators to inhibit the tumor progression in vitro and in vivo.
Eur J Med Chem
; 192: 112153, 2020 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-32135407
19.
Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway.
Eur J Med Chem
; 203: 112618, 2020 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32682200
20.
Mechanisms of synergistic neurotoxicity induced by two high risk pesticide residues - Chlorpyrifos and Carbofuran via oxidative stress.
Toxicol In Vitro
; 54: 338-344, 2019 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30385350