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1.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 spike.

Yamasoba, Daichi; Kimura, Izumi; Nasser, Hesham; Morioka, Yuhei; Nao, Naganori; Ito, Jumpei; Uriu, Keiya; Tsuda, Masumi; Zahradnik, Jiri; Shirakawa, Kotaro; Suzuki, Rigel; Kishimoto, Mai; Kosugi, Yusuke; Kobiyama, Kouji; Hara, Teppei; Toyoda, Mako; Tanaka, Yuri L; Butlertanaka, Erika P; Shimizu, Ryo; Ito, Hayato; Wang, Lei; Oda, Yoshitaka; Orba, Yasuko; Sasaki, Michihito; Nagata, Kayoko; Yoshimatsu, Kumiko; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Kuramochi, Jin; Seki, Motoaki; Fujiki, Ryoji; Kaneda, Atsushi; Shimada, Tadanaga; Nakada, Taka-Aki; Sakao, Seiichiro; Suzuki, Takuji; Ueno, Takamasa; Takaori-Kondo, Akifumi; Ishii, Ken J; Schreiber, Gideon; Sawa, Hirofumi; Saito, Akatsuki; Irie, Takashi; Tanaka, Shinya; Matsuno, Keita; Fukuhara, Takasuke; Ikeda, Terumasa; Sato, Kei.

Cell ; 185(12): 2103-2115.e19, 2022 06 09.

Artículo en Inglés | MEDLINE | ID: mdl-35568035

2.

Virological characteristics of the SARS-CoV-2 Omicron BA.2 subvariants, including BA.4 and BA.5.

Kimura, Izumi; Yamasoba, Daichi; Tamura, Tomokazu; Nao, Naganori; Suzuki, Tateki; Oda, Yoshitaka; Mitoma, Shuya; Ito, Jumpei; Nasser, Hesham; Zahradnik, Jiri; Uriu, Keiya; Fujita, Shigeru; Kosugi, Yusuke; Wang, Lei; Tsuda, Masumi; Kishimoto, Mai; Ito, Hayato; Suzuki, Rigel; Shimizu, Ryo; Begum, Mst Monira; Yoshimatsu, Kumiko; Kimura, Kanako Terakado; Sasaki, Jiei; Sasaki-Tabata, Kaori; Yamamoto, Yuki; Nagamoto, Tetsuharu; Kanamune, Jun; Kobiyama, Kouji; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Shirakawa, Kotaro; Takaori-Kondo, Akifumi; Kuramochi, Jin; Schreiber, Gideon; Ishii, Ken J; Hashiguchi, Takao; Ikeda, Terumasa; Saito, Akatsuki; Fukuhara, Takasuke; Tanaka, Shinya; Matsuno, Keita; Sato, Kei.

Cell ; 185(21): 3992-4007.e16, 2022 10 13.

Artículo en Inglés | MEDLINE | ID: mdl-36198317

3.

Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant.

Suzuki, Rigel; Yamasoba, Daichi; Kimura, Izumi; Wang, Lei; Kishimoto, Mai; Ito, Jumpei; Morioka, Yuhei; Nao, Naganori; Nasser, Hesham; Uriu, Keiya; Kosugi, Yusuke; Tsuda, Masumi; Orba, Yasuko; Sasaki, Michihito; Shimizu, Ryo; Kawabata, Ryoko; Yoshimatsu, Kumiko; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Sawa, Hirofumi; Ikeda, Terumasa; Irie, Takashi; Matsuno, Keita; Tanaka, Shinya; Fukuhara, Takasuke; Sato, Kei.

Nature ; 603(7902): 700-705, 2022 03.

Artículo en Inglés | MEDLINE | ID: mdl-35104835

4.

Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation.

Saito, Akatsuki; Irie, Takashi; Suzuki, Rigel; Maemura, Tadashi; Nasser, Hesham; Uriu, Keiya; Kosugi, Yusuke; Shirakawa, Kotaro; Sadamasu, Kenji; Kimura, Izumi; Ito, Jumpei; Wu, Jiaqi; Iwatsuki-Horimoto, Kiyoko; Ito, Mutsumi; Yamayoshi, Seiya; Loeber, Samantha; Tsuda, Masumi; Wang, Lei; Ozono, Seiya; Butlertanaka, Erika P; Tanaka, Yuri L; Shimizu, Ryo; Shimizu, Kenta; Yoshimatsu, Kumiko; Kawabata, Ryoko; Sakaguchi, Takemasa; Tokunaga, Kenzo; Yoshida, Isao; Asakura, Hiroyuki; Nagashima, Mami; Kazuma, Yasuhiro; Nomura, Ryosuke; Horisawa, Yoshihito; Yoshimura, Kazuhisa; Takaori-Kondo, Akifumi; Imai, Masaki; Tanaka, Shinya; Nakagawa, So; Ikeda, Terumasa; Fukuhara, Takasuke; Kawaoka, Yoshihiro; Sato, Kei.

Nature ; 602(7896): 300-306, 2022 02.

Artículo en Inglés | MEDLINE | ID: mdl-34823256

5.

A rapid and versatile reverse genetics approach for generating recombinant positive-strand RNA viruses that use IRES-mediated translation.

Tamura, Tomokazu; Yamamoto, Hirotaka; Ogino, Saho; Morioka, Yuhei; Tsujino, Shuhei; Suzuki, Rigel; Hiono, Takahiro; Suzuki, Saori; Isoda, Norikazu; Sakoda, Yoshihiro; Fukuhara, Takasuke.

J Virol ; 98(3): e0163823, 2024 Mar 19.

Artículo en Inglés | MEDLINE | ID: mdl-38353536

6.

Increased flexibility of the SARS-CoV-2 RNA-binding site causes resistance to remdesivir.

Torii, Shiho; Kim, Kwang Su; Koseki, Jun; Suzuki, Rigel; Iwanami, Shoya; Fujita, Yasuhisa; Jeong, Yong Dam; Ito, Jumpei; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Sato, Kei; Matsuura, Yoshiharu; Shimamura, Teppei; Iwami, Shingo; Fukuhara, Takasuke.

PLoS Pathog ; 19(3): e1011231, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36972312

7.

Prolonged shedding of viable SARS-CoV-2 in immunocompromised patients with haematological malignancies: A prospective study.

Ichikawa, Takaya; Tamura, Tomokazu; Takahata, Mutsumi; Ishio, Takashi; Ibata, Makoto; Kasahara, Ikumi; Minauchi, Koichiro; Yamamoto, Satoshi; Teshima, Takanori; Fukuhara, Takasuke.

Br J Haematol ; 204(3): 815-820, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-37795527

8.

Generation of recombinant viruses directly from clinical specimens of COVID-19 patients.

Yamamoto, Hirotaka; Tamura, Tomokazu; Ichikawa, Takaya; Taguchi, Yudai; Mori, Kento; Oguri, Satoshi; Suzuki, Rigel; Suzuki, Saori; Teshima, Takanori; Fukuhara, Takasuke.

J Clin Microbiol ; : e0004224, 2024 Jun 14.

Artículo en Inglés | MEDLINE | ID: mdl-38874339

9.

Multiple mutations of SARS-CoV-2 Omicron BA.2 variant orchestrate its virological characteristics.

Kimura, Izumi; Yamasoba, Daichi; Nasser, Hesham; Ito, Hayato; Zahradnik, Jiri; Wu, Jiaqi; Fujita, Shigeru; Uriu, Keiya; Sasaki, Jiei; Tamura, Tomokazu; Suzuki, Rigel; Deguchi, Sayaka; Plianchaisuk, Arnon; Yoshimatsu, Kumiko; Kazuma, Yasuhiro; Mitoma, Shuya; Schreiber, Gideon; Asakura, Hiroyuki; Nagashima, Mami; Sadamasu, Kenji; Yoshimura, Kazuhisa; Takaori-Kondo, Akifumi; Ito, Jumpei; Shirakawa, Kotaro; Takayama, Kazuo; Irie, Takashi; Hashiguchi, Takao; Nakagawa, So; Fukuhara, Takasuke; Saito, Akatsuki; Ikeda, Terumasa; Sato, Kei.

J Virol ; 97(10): e0101123, 2023 10 31.

Artículo en Inglés | MEDLINE | ID: mdl-37796123

10.

Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses.

Tamura, Tomokazu; Torii, Shiho; Kajiwara, Kentaro; Anzai, Itsuki; Fujioka, Yoichiro; Noda, Kisho; Taguwa, Shuhei; Morioka, Yuhei; Suzuki, Rigel; Fauzyah, Yuzy; Ono, Chikako; Ohba, Yusuke; Okada, Masato; Fukuhara, Takasuke; Matsuura, Yoshiharu.

PLoS Pathog ; 18(6): e1010593, 2022 06.

Artículo en Inglés | MEDLINE | ID: mdl-35658055

11.

Involvement of SARS-CoV-2 accessory proteins in immunopathogenesis.

Ito, Hayato; Tamura, Tomokazu; Wang, Lei; Mori, Kento; Tsuda, Masumi; Suzuki, Rigel; Suzuki, Saori; Yoshimatsu, Kumiko; Tanaka, Shinya; Fukuhara, Takasuke.

Microbiol Immunol ; 2024 Jun 04.

Artículo en Inglés | MEDLINE | ID: mdl-38837257

12.

Impact of Imprinted Immunity Induced by mRNA Vaccination in an Experimental Animal Model.

Fujita, Shigeru; Uriu, Keiya; Pan, Lin; Nao, Naganori; Tabata, Koshiro; Kishimoto, Mai; Itakura, Yukari; Sawa, Hirofumi; Kida, Izumi; Tamura, Tomokazu; Fukuhara, Takasuke; Ito, Jumpei; Matsuno, Keita; Sato, Kei.

J Infect Dis ; 228(8): 1060-1065, 2023 10 18.

Artículo en Inglés | MEDLINE | ID: mdl-37369369

13.

Evaluation of Broad Anti-Coronavirus Activity of Autophagy-Related Compounds Using Human Airway Organoids.

Hashimoto, Rina; Tamura, Tomokazu; Watanabe, Yukio; Sakamoto, Ayaka; Yasuhara, Naoko; Ito, Hayato; Nakano, Masahiro; Fuse, Hiromitsu; Ohta, Akira; Noda, Takeshi; Matsumura, Yasufumi; Nagao, Miki; Yamamoto, Takuya; Fukuhara, Takasuke; Takayama, Kazuo.

Mol Pharm ; 20(4): 2276-2287, 2023 04 03.

Artículo en Inglés | MEDLINE | ID: mdl-36946991

14.

Smoking enhances the expression of angiotensin-converting enzyme 2 involved in the efficiency of severe acute respiratory syndrome coronavirus 2 infection.

Suzuki, Rigel; Ono, Yuki; Noshita, Koji; Kim, Kwang Su; Ito, Hayato; Morioka, Yuhei; Tamura, Tomokazu; Okuzaki, Daisuke; Tagawa, Tetsuzo; Takenaka, Tomoyoshi; Yoshizumi, Tomoharu; Shimamura, Teppei; Iwami, Shingo; Fukuhara, Takasuke.

Microbiol Immunol ; 67(1): 22-31, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-36258658

15.

Various miRNAs compensate the role of miR-122 on HCV replication.

Ono, Chikako; Fukuhara, Takasuke; Li, Songling; Wang, Jian; Sato, Asuka; Izumi, Takuma; Fauzyah, Yuzy; Yamamoto, Takuya; Morioka, Yuhei; Dokholyan, Nikolay V; Standley, Daron M; Matsuura, Yoshiharu.

PLoS Pathog ; 16(6): e1008308, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-32574204

16.

Antiviral activity of ciclesonide acetal derivatives blocking SARS-CoV-2 RNA replication.

Tsuji, Genichiro; Nakajima, Shogo; Watashi, Koichi; Torii, Shiho; Suzuki, Rigel; Fukuhara, Takasuke; Ohoka, Nobumichi; Inoue, Takao; Demizu, Yosuke.

J Pharmacol Sci ; 149(3): 81-84, 2022 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-35641031

17.

Host ESCRT factors are recruited during chikungunya virus infection and are required for the intracellular viral replication cycle.

Torii, Shiho; Orba, Yasuko; Sasaki, Michihito; Tabata, Koshiro; Wada, Yuji; Carr, Michael; Hobson-Peters, Jody; Hall, Roy A; Takada, Ayato; Fukuhara, Takasuke; Matsuura, Yoshiharu; Hall, William W; Sawa, Hirofumi.

J Biol Chem ; 295(23): 7941-7957, 2020 06 05.

Artículo en Inglés | MEDLINE | ID: mdl-32341071

18.

ISGylation of Hepatitis C Virus NS5A Protein Promotes Viral RNA Replication via Recruitment of Cyclophilin A.

Abe, Takayuki; Minami, Nanae; Bawono, Rheza Gandi; Matsui, Chieko; Deng, Lin; Fukuhara, Takasuke; Matsuura, Yoshiharu; Shoji, Ikuo.

J Virol ; 94(20)2020 09 29.

Artículo en Inglés | MEDLINE | ID: mdl-32727878

19.

In Vivo Dynamics of Reporter Flaviviridae Viruses.

Tamura, Tomokazu; Igarashi, Manabu; Enkhbold, Bazarragchaa; Suzuki, Tatsuya; Okamatsu, Masatoshi; Ono, Chikako; Mori, Hiroyuki; Izumi, Takuma; Sato, Asuka; Fauzyah, Yuzy; Okamoto, Toru; Sakoda, Yoshihiro; Fukuhara, Takasuke; Matsuura, Yoshiharu.

J Virol ; 93(22)2019 11 15.

Artículo en Inglés | MEDLINE | ID: mdl-31462560

20.

USP15 Participates in Hepatitis C Virus Propagation through Regulation of Viral RNA Translation and Lipid Droplet Formation.

Kusakabe, Shinji; Suzuki, Tatsuya; Sugiyama, Yukari; Haga, Saori; Horike, Kanako; Tokunaga, Makoto; Hirano, Junki; Zhang, He; Chen, David Virya; Ishiga, Hanako; Komoda, Yasumasa; Ono, Chikako; Fukuhara, Takasuke; Yamamoto, Masahiro; Ikawa, Masahito; Satoh, Takashi; Akira, Shizuo; Tanaka, Tomohisa; Moriishi, Kohji; Fukai, Moto; Taketomi, Akinobu; Yoshio, Sachiyo; Kanto, Tatsuya; Suzuki, Tetsuro; Okamoto, Toru; Matsuura, Yoshiharu.

J Virol ; 93(6)2019 03 15.

Artículo en Inglés | MEDLINE | ID: mdl-30626683

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