Detalles de la búsqueda
1.
Morphological alterations in corneal nerves of patients with dry eye and associated biomarkers.
Exp Eye Res
; 230: 109438, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-36933693
2.
A phase 1 study to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of danuglipron (PF-06882961), an oral small-molecule glucagon-like peptide-1 receptor agonist, in Japanese adults with type 2 diabetes mellitus.
Diabetes Obes Metab
; 25(3): 805-814, 2023 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-36433713
3.
A phase 1 multiple-ascending dose study of tirzepatide in Japanese participants with type 2 diabetes.
Diabetes Obes Metab
; 24(2): 239-246, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34647404
4.
Prediction of Recurrence in Patients with Stage III Colon Cancer Using Conventional Clinicopathological Factors and Peripheral Blood Test Data: A New Analysis with Artificial Intelligence.
Oncology
; 99(5): 318-326, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33626534
5.
Pharmacokinetics of indacaterol, glycopyrronium and mometasone furoate administered as an inhaled fixed-dose combination in Japanese and Caucasian healthy subjects.
BMC Pulm Med
; 21(1): 18, 2021 Jan 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-33413291
6.
A drug-drug interaction study of a novel, selective urate reabsorption inhibitor dotinurad and the non-steroidal anti-inflammatory drug oxaprozin in healthy adult males.
Clin Exp Nephrol
; 24(Suppl 1): 36-43, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-32076889
7.
Dotinurad: a clinical pharmacokinetic study of a novel, selective urate reabsorption inhibitor in subjects with hepatic impairment.
Clin Exp Nephrol
; 24(Suppl 1): 25-35, 2020 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-31760530
8.
Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers.
Br J Clin Pharmacol
; 85(7): 1454-1463, 2019 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-30845361
9.
Correction to: Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers.
Pharm Res
; 36(4): 55, 2019 02 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-30790061
10.
Effect of short-term treatment with sitagliptin or glibenclamide on daily glucose fluctuation in drug-naïve Japanese patients with type 2 diabetes mellitus.
Diabetes Obes Metab
; 20(9): 2274-2281, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29770541
11.
Comparative Study of the Dose-Dependence of OATP1B Inhibition by Rifampicin Using Probe Drugs and Endogenous Substrates in Healthy Volunteers.
Pharm Res
; 35(7): 138, 2018 05 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29748935
12.
A Clinical Cassette Dosing Study for Evaluating the Contribution of Hepatic OATPs and CYP3A to Drug-Drug Interactions.
Pharm Res
; 34(8): 1570-1583, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28484975
13.
Investigation of Glycochenodeoxycholate Sulfate and Chenodeoxycholate Glucuronide as Surrogate Endogenous Probes for Drug Interaction Studies of OATP1B1 and OATP1B3 in Healthy Japanese Volunteers.
Pharm Res
; 34(8): 1601-1614, 2017 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-28550384
14.
Pharmacokinetics of QMF149 in Japanese versus Caucasian subjects: an open-label, randomized phase I study.
Int J Clin Pharmacol Ther
; 53(5): 398-407, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25740265
15.
Pharmacokinetic and pharmacodynamic interaction of vildagliptin and voglibose in Japanese patients with Type 2 diabetes.
Int J Clin Pharmacol Ther
; 51(8): 641-51, 2013 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-23782587
16.
A multi-purpose Japanese phase I study in the global development of vupanorsen: Randomized, placebo-controlled, single-ascending dose study in adults.
Clin Transl Sci
; 16(5): 886-897, 2023 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-37002654
17.
Pharmacokinetics, Safety, and Tolerability of NPC-21, an Anti-Cytomegalovirus Monoclonal Antibody, in Healthy Japanese and White Adult Men: A Randomized, Placebo-Controlled, First-in-Human Phase 1 Study.
Clin Pharmacol Drug Dev
; 11(6): 707-716, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-34989174
18.
Pharmacokinetics, Safety, and Tolerability of Letermovir Following Single- and Multiple-Dose Administration in Healthy Japanese Subjects.
Clin Pharmacol Drug Dev
; 11(8): 938-948, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35238179
19.
Effect of Cyclosporin A and Impact of Dose Staggering on OATP1B1/1B3 Endogenous Substrates and Drug Probes for Assessing Clinical Drug Interactions.
Clin Pharmacol Ther
; 111(6): 1315-1323, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35292967
20.
Physiologically-based pharmacokinetic model-based translation of OATP1B-mediated drug-drug interactions from coproporphyrin I to probe drugs.
Clin Transl Sci
; 15(6): 1519-1531, 2022 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-35421902