Detalles de la búsqueda
1.
Synthesis, resolution, and absolute configuration determination of a vicinal amino alcohol with axial chirality. Application to the synthesis of new box and pybox ligands.
Chirality
; 34(8): 1140-1150, 2022 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-35609966
2.
Design, synthesis and structure-activity evaluation of novel 2-pyridone-based inhibitors of α-synuclein aggregation with potentially improved BBB permeability.
Bioorg Chem
; 117: 105472, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34775206
3.
Asymmetric synthesis of (1R,5S)-2-methyl-6,7-benzomorphan via Aza-Prins reaction.
Chirality
; 33(9): 543-548, 2021 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-34279050
4.
Selective Targeting of Human and Animal Pathogens of the Helicobacter Genus by Flavodoxin Inhibitors: Efficacy, Synergy, Resistance and Mechanistic Studies.
Int J Mol Sci
; 22(18)2021 Sep 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34576300
5.
Debenzylative Cycloetherification as a Synthetic Tool in the Diastereoselective Synthesis of 3,6-Disubstituted Hexahydro-2H-furo[3,2-b]pyrroles, PDE1 Enzyme Inhibitors with an Antiproliferative Effect on Melanoma Cells.
J Org Chem
; 85(9): 5941-5951, 2020 05 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32248689
6.
A pyrene-inhibitor fluorescent probe with large Stokes shift for the staining of Aß1-42, α-synuclein, and amylin amyloid fibrils as well as amyloid-containing Staphylococcus aureus biofilms.
Anal Bioanal Chem
; 411(1): 251-265, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30411148
7.
Diastereoselective Construction of the 6-Oxa-2-azabicyclo[3.2.1]octane Scaffold from Chiral α-Hydroxyaldehyde Derivatives by the Aza-Prins Reaction.
J Org Chem
; 82(15): 8048-8057, 2017 08 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-28715633
8.
Synthesis of new pyrrolidine-based organocatalysts and study of their use in the asymmetric Michael addition of aldehydes to nitroolefins.
Beilstein J Org Chem
; 13: 612-619, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28487754
9.
A novel pan-negative-gating modulator of KCa2/3 channels, fluoro-di-benzoate, RA-2, inhibits endothelium-derived hyperpolarization-type relaxation in coronary artery and produces bradycardia in vivo.
Mol Pharmacol
; 87(2): 338-48, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25468883
10.
Chiral iminoesters derived from D-glyceraldehyde in [3 + 2] cycloaddition reactions. Asymmetric synthesis of a key intermediate in the synthesis of neuramidinase inhibitors.
J Org Chem
; 78(22): 11404-13, 2013 Nov 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24143968
11.
Organocatalyzed enantioselective desymmetrization of diols in the preparation of chiral building blocks.
Chemistry
; 18(44): 13920-35, 2012 Oct 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-23033139
12.
Stereoselective synthesis and biological evaluation of D-fagomine, D-3-epi-fagomine and D-3,4-epi-fagomine analogs from D-glyceraldehyde acetonide as a common building block.
Org Biomol Chem
; 10(46): 9278-86, 2012 Dec 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-23104470
13.
Recent advances in enantioselective organocatalyzed anhydride desymmetrization and its application to the synthesis of valuable enantiopure compounds.
Chem Soc Rev
; 40(11): 5564-87, 2011 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-21731960
14.
Switch in regioselectivity of epoxide ring-opening by changing the organometallic reagent.
Org Biomol Chem
; 9(23): 8155-62, 2011 Dec 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-22015982
15.
Stereocontrolled synthesis of orthogonally protected 2-substituted 4-aminopiperidines.
Org Biomol Chem
; 7(14): 2912-8, 2009 Jul 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-19582301
16.
Stereoselective synthesis and biological evaluation as inhibitors of hepatitis C virus RNA polymerase of GSK3082 analogues with structural diversity at the 5-position.
Eur J Med Chem
; 171: 401-419, 2019 Jun 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-30928711
17.
Asymmetric homologation of ketones. A new entry to orthogonally protected (2R,4R)-piperidine-2,4-dicarboxylic acid.
J Org Chem
; 73(21): 8594-7, 2008 Nov 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-18826279
18.
Unexpected epimerization at C2 in the Horner-Wadsworth-Emmons reaction of chiral 2-substituted-4-oxopiperidines.
Chem Commun (Camb)
; (32): 3420-2, 2006 Aug 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-16896481
19.
Vascular Reactivity Profile of Novel KCa 3.1-Selective Positive-Gating Modulators in the Coronary Vascular Bed.
Basic Clin Pharmacol Toxicol
; 119(2): 184-92, 2016 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-26821335
20.
High-performance liquid chromatographic enantioseparation of unusual amino acid derivatives with axial chirality on polysaccharide-based chiral stationary phases.
J Chromatogr A
; 1390: 78-85, 2015 Apr 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-25748541