Detalles de la búsqueda
1.
Novel 5,6-disubstituted pyrrolo[2,3-d]pyrimidine derivatives as broad spectrum antiproliferative agents: Synthesis, cell based assays, kinase profile and molecular docking study.
Bioorg Med Chem
; 26(21): 5596-5611, 2018 11 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30385226
2.
Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain.
J Enzyme Inhib Med Chem
; 33(1): 1460-1471, 2018 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-30231778
3.
In silico quantitative structure-activity relationship studies on P-gp modulators of tetrahydroisoquinoline-ethyl-phenylamine series.
BMC Struct Biol
; 11: 5, 2011 Jan 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-21269449
4.
Structure-activity relationships of fluorene compounds inhibiting HCV variants.
Antiviral Res
; 174: 104678, 2020 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31862501
5.
PyrPeg, a Blood-Brain-Barrier-Penetrating Two-Photon Imaging Probe, Selectively Detects Neuritic Plaques, Not Tau Aggregates.
ACS Chem Neurosci
; 11(12): 1801-1810, 2020 06 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-32421307
6.
3-Carene, a Phytoncide from Pine Tree Has a Sleep-enhancing Effect by Targeting the GABAA-benzodiazepine Receptors.
Exp Neurobiol
; 28(5): 593-601, 2019 Oct 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-31698551
7.
Development of Oxadiazole-Based ODZ10117 as a Small-Molecule Inhibitor of STAT3 for Targeted Cancer Therapy.
J Clin Med
; 8(11)2019 Nov 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-31684051
8.
Development of an Aryloxazole Derivative as a Brain-Permeable Anti-Glioblastoma Agent.
Pharmaceutics
; 11(10)2019 Sep 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-31569420
9.
Identification of crizotinib derivatives as potent SHIP2 inhibitors for the treatment of Alzheimer's disease.
Eur J Med Chem
; 157: 405-422, 2018 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-30103190
10.
A novel tropomyosin-related kinase A inhibitor, KK5101 to treat pancreatic cancer.
Cancer Lett
; 426: 25-36, 2018 07 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-29605512
11.
Insights into the binding modes of CC chemokine receptor 4 (CCR4) inhibitors: a combined approach involving homology modelling, docking, and molecular dynamics simulation studies.
Mol Biosyst
; 11(2): 618-34, 2015 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-25474265
12.
Finding new scaffolds of JAK3 inhibitors in public database: 3D-QSAR models & shape-based screening.
Arch Pharm Res
; 38(11): 2008-19, 2015 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-25956696
13.
In silico characterization of binding mode of CCR8 inhibitor: homology modeling, docking and membrane based MD simulation study.
J Biomol Struct Dyn
; 33(11): 2491-510, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25617117
14.
Modeling study of phenylsulfonylfuroxan derivatives as P-gp inhibitors: a combined approach of CoMFA, CoMSIA and HQSAR.
Anticancer Agents Med Chem
; 14(7): 1019-30, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24066798
15.
The nociceptin receptor (NOPR) and its interaction with clinically important agonist molecules: a membrane molecular dynamics simulation study.
Mol Biosyst
; 10(12): 3188-98, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-25259728
16.
In silico study on indole derivatives as anti HIV-1 agents: a combined docking, molecular dynamics and 3D-QSAR study.
Arch Pharm Res
; 37(8): 1001-15, 2014 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-24338530
17.
A Protoberberine derivative HWY336 selectively inhibits MKK4 and MKK7 in mammalian cells: the importance of activation loop on selectivity.
PLoS One
; 9(4): e91037, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-24759688
18.
Novel ionophores with 2n-crown-n topology: anion sensing via pure aliphatic C-H···anion hydrogen bonding.
Org Lett
; 16(2): 334-7, 2014 Jan 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-24377324
19.
Theoretical characterization of galanin receptor type 3 (Gal3 ) and its interaction with agonist (GALANIN) and antagonists (SNAP 37889 and SNAP 398299): an in silico analysis.
Chem Biol Drug Des
; 81(6): 757-74, 2013 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-23461969
20.
Computational modeling of human coreceptor CCR5 antagonist as a HIV-1 entry inhibitor: using an integrated homology modeling, docking, and membrane molecular dynamics simulation analysis approach.
J Biomol Struct Dyn
; 31(11): 1251-76, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23153179