Detalles de la búsqueda
1.
Clusters of apoptotic signaling molecule-enriched rafts, CASMERs: membrane platforms for protein assembly in Fas/CD95 signaling and targets in cancer therapy.
Biochem Soc Trans
; 50(3): 1105-1118, 2022 06 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-35587168
2.
Upregulated expression and function of the α4ß1 integrin in multiple myeloma cells resistant to bortezomib.
J Pathol
; 252(1): 29-40, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32501543
3.
Lipid rafts as signaling hubs in cancer cell survival/death and invasion: implications in tumor progression and therapy: Thematic Review Series: Biology of Lipid Rafts.
J Lipid Res
; 61(5): 611-635, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-33715811
4.
Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring.
Bioorg Chem
; 98: 103755, 2020 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-32200330
5.
Antitumor activity of Lepidium latifolium and identification of the epithionitrile 1-cyano-2,3-epithiopropane as its major active component.
Mol Carcinog
; 57(3): 347-360, 2018 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-29073716
6.
Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.
Chemistry
; 23(7): 1676-1685, 2017 Jan 31.
Artículo
en Inglés
| MEDLINE | ID: mdl-27885731
7.
Lipid rafts and raft-mediated supramolecular entities in the regulation of CD95 death receptor apoptotic signaling.
Apoptosis
; 20(5): 584-606, 2015 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-25702154
8.
Drug uptake, lipid rafts, and vesicle trafficking modulate resistance to an anticancer lysophosphatidylcholine analogue in yeast.
J Biol Chem
; 288(12): 8405-8418, 2013 Mar 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-23335509
9.
Suppression of metastatic organ colonization and antiangiogenic activity of the orally bioavailable lipid raft-targeted alkylphospholipid edelfosine.
Biomed Pharmacother
; 171: 116149, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38266621
10.
Antitumor activity of alkylphospholipid edelfosine in prostate cancer models and endoplasmic reticulum targeting.
Biomed Pharmacother
; 167: 115436, 2023 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-37683591
11.
Identification of new FK866 analogues with potent anticancer activity against pancreatic cancer.
Eur J Med Chem
; 239: 114504, 2022 Sep 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-35724566
12.
Involvement of mitochondrial and B-RAF/ERK signaling pathways in berberine-induced apoptosis in human melanoma cells.
Anticancer Drugs
; 22(6): 507-18, 2011 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-21527846
13.
Mitochondrial Targeting Involving Cholesterol-Rich Lipid Rafts in the Mechanism of Action of the Antitumor Ether Lipid and Alkylphospholipid Analog Edelfosine.
Pharmaceutics
; 13(5)2021 May 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-34065546
14.
Direct Endoplasmic Reticulum Targeting by the Selective Alkylphospholipid Analog and Antitumor Ether Lipid Edelfosine as a Therapeutic Approach in Pancreatic Cancer.
Cancers (Basel)
; 13(16)2021 Aug 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34439330
15.
Lipid Raft Isolation by Sucrose Gradient Centrifugation and Visualization of Raft-Located Proteins by Fluorescence Microscopy: The Use of Combined Techniques to Assess Fas/CD95 Location in Rafts During Apoptosis Triggering.
Methods Mol Biol
; 2187: 147-186, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-32770506
16.
Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release.
Sci Rep
; 11(1): 12574, 2021 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-34131176
17.
Methylsulfanylpyridine based diheteroaryl isocombretastatin analogs as potent anti-proliferative agents.
Eur J Med Chem
; 209: 112933, 2021 Jan 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33328100
18.
Induction of Apoptosis in Human Pancreatic Cancer Stem Cells by the Endoplasmic Reticulum-Targeted Alkylphospholipid Analog Edelfosine and Potentiation by Autophagy Inhibition.
Cancers (Basel)
; 13(23)2021 Dec 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-34885233
19.
Intracellular triggering of Fas aggregation and recruitment of apoptotic molecules into Fas-enriched rafts in selective tumor cell apoptosis.
J Exp Med
; 200(3): 353-65, 2004 Aug 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-15289504
20.
Antitumor alkyl ether lipid edelfosine: tissue distribution and pharmacokinetic behavior in healthy and tumor-bearing immunosuppressed mice.
Clin Cancer Res
; 15(3): 858-64, 2009 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-19188156