Detalles de la búsqueda
1.
ATLANTIS: a Phase III study of lurbinectedin/doxorubicin versus topotecan or cyclophosphamide/doxorubicin/vincristine in patients with small-cell lung cancer who have failed one prior platinum-containing line.
Future Oncol
; 15(3): 231-239, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30362375
2.
Binding of eEF1A2 to the RNA-dependent protein kinase PKR modulates its activity and promotes tumour cell survival.
Br J Cancer
; 119(11): 1410-1420, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30420615
3.
Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells.
BMC Cancer
; 18(1): 164, 2018 02 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29415678
4.
Lurbinectedin reduces tumour-associated macrophages and the inflammatory tumour microenvironment in preclinical models.
Br J Cancer
; 117(5): 628-638, 2017 Aug 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-28683469
5.
Antitumour activity of trabectedin in myelodysplastic/myeloproliferative neoplasms.
Br J Cancer
; 116(3): 335-343, 2017 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-28072764
6.
Concomitant resistance and early-breast cancer: should we change treatment strategies?
Cancer Metastasis Rev
; 33(1): 271-83, 2014 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-24346157
7.
Nibrin is a marker of clinical outcome in patients with advanced serous ovarian cancer treated in the phase III OVA-301 trial.
Gynecol Oncol
; 132(1): 176-80, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24211400
8.
Trabectedin and plitidepsin: drugs from the sea that strike the tumor microenvironment.
Mar Drugs
; 12(2): 719-33, 2014 Jan 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-24473171
9.
Comparison of in vitro and in vivo biological effects of trabectedin, lurbinectedin (PM01183) and Zalypsis® (PM00104).
Int J Cancer
; 133(9): 2024-33, 2013 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-23588839
10.
Temperature-induced melting of double-stranded DNA in the absence and presence of covalently bonded antitumour drugs: insight from molecular dynamics simulations.
Nucleic Acids Res
; 39(18): 8248-57, 2011 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21727089
11.
Hypoxia reduces the efficiency of elisidepsin by inhibiting hydroxylation and altering the structure of lipid rafts.
Mar Drugs
; 11(12): 4858-75, 2013 Dec 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-24317474
12.
Predictive factors of sensitivity to elisidepsin, a novel Kahalalide F-derived marine compound.
Mar Drugs
; 11(3): 944-59, 2013 Mar 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-23519149
13.
c-Jun N-terminal kinase phosphorylation is a biomarker of plitidepsin activity.
Mar Drugs
; 11(5): 1677-92, 2013 May 21.
Artículo
en Inglés
| MEDLINE | ID: mdl-23697951
14.
The cytotoxic activity of Aplidin in chronic lymphocytic leukemia (CLL) is mediated by a direct effect on leukemic cells and an indirect effect on monocyte-derived cells.
Invest New Drugs
; 30(5): 1830-40, 2012 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-21887502
15.
Analysis of transcriptomic responses to SARS-CoV-2 reveals plausible defective pathways responsible for increased susceptibility to infection and complications and helps to develop fast-track repositioning of drugs against COVID-19.
Comput Biol Med
; 149: 106029, 2022 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-36067633
16.
Zalypsis: a novel marine-derived compound with potent antimyeloma activity that reveals high sensitivity of malignant plasma cells to DNA double-strand breaks.
Blood
; 113(16): 3781-91, 2009 Apr 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-19020308
17.
Zalypsis has in vitro activity in acute myeloid blasts and leukemic progenitor cells through the induction of a DNA damage response.
Haematologica
; 96(5): 687-95, 2011 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-21330323
18.
Why we do what we do. A brief analysis of cancer therapies.
EXCLI J
; 19: 1401-1413, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33312104
19.
Lessons from Hippocrates: Time to Change the Cancer Paradigm.
Int J Chronic Dis
; 2020: 4715426, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-32566644
20.
Deep Neural Frameworks Improve the Accuracy of General Practitioners in the Classification of Pigmented Skin Lesions.
Diagnostics (Basel)
; 10(11)2020 Nov 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-33218060