Detalles de la búsqueda
1.
Design, Synthesis and Evaluation of Fluorescent Properties of Benzothiazole Derivatives.
Chemphyschem
; 24(17): e202300159, 2023 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37349282
2.
Theoretical study and application of 2-phenyl-1,3,4-thiadiazole derivatives with optical and inhibitory activity against SHP1.
Phys Chem Chem Phys
; 24(2): 861-874, 2022 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-34908073
3.
Synthesis and Biochemical Evaluation of 8H-Indeno[1,2-d]thiazole Derivatives as Novel SARS-CoV-2 3CL Protease Inhibitors.
Molecules
; 27(10)2022 May 23.
Artículo
en Inglés
| MEDLINE | ID: mdl-35630836
4.
Synthesis and biological evaluation of 2,5-diaryl-1,3,4-oxadiazole derivatives as novel Src homology 2 domain-containing protein tyrosine phosphatase 2 (SHP2) inhibitors.
Bioorg Chem
; 116: 105384, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34601294
5.
Synthesis and biological evaluation of heterocyclic bis-aryl amides as novel Src homology 2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.
Bioorg Med Chem Lett
; 30(11): 127170, 2020 06 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32273218
6.
Tim3/galectin-9 alleviates the inflammation of TAO patients via suppressing Akt/NF-kB signaling pathway.
Biochem Biophys Res Commun
; 491(4): 966-972, 2017 09 30.
Artículo
en Inglés
| MEDLINE | ID: mdl-28756232
7.
Benzo[c][1,2,5]thiadiazole derivatives: A new class of potent Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2) inhibitors.
Bioorg Med Chem Lett
; 27(23): 5154-5157, 2017 12 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-29100798
8.
Design, synthesis and in vitro activity of phidianidine B derivatives as novel PTP1B inhibitors with specific selectivity.
Bioorg Med Chem Lett
; 26(3): 778-781, 2016 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-26774579
9.
Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUB inhibition, is synergistic with bortezomib against multiple myeloma cell growth.
Biochim Biophys Acta
; 1840(6): 2004-13, 2014 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-24534329
10.
Chlorabietols A-C, Phloroglucinol-Diterpene Adducts from the Chloranthaceae Plant Chloranthus oldhamii.
J Org Chem
; 80(21): 11080-5, 2015 Nov 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-26444099
11.
PTP1B inhibitors from stems of Angelica keiskei (Ashitaba).
Bioorg Med Chem Lett
; 25(10): 2028-32, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25891102
12.
Design and synthesis of novel 1,2-dithiolan-4-yl benzoate derivatives as PTP1B inhibitors.
Bioorg Med Chem Lett
; 25(10): 2211-6, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25872983
13.
New Isoprenylated Phenolic Compounds from Morus laevigata.
Chem Biodivers
; 12(6): 937-45, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-26080739
14.
Brominated polyunsaturated lipids with protein tyrosine phosphatase-1B inhibitory activity from Chinese marine sponge Xestospongia testudinaria.
J Asian Nat Prod Res
; 17(8): 861-6, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25832997
15.
Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors.
Bioorg Med Chem Lett
; 24(8): 1889-94, 2014 Apr 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24684845
16.
Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhibitors.
Org Biomol Chem
; 12(21): 3441-5, 2014 Jun 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-24752625
17.
4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B.
Bioorg Med Chem
; 22(14): 3670-83, 2014 Jul 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-24906513
18.
Synthesis, Fluorescence, and Bioactivity of Novel Isatin Derivatives.
J Phys Chem B
; 2024 Jun 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-38875519
19.
Novel imidazo[1,2,4] triazole derivatives: Synthesis, fluorescence, bioactivity for SHP1.
Eur J Med Chem
; 265: 116027, 2024 Feb 05.
Artículo
en Inglés
| MEDLINE | ID: mdl-38128236
20.
The first synthesis of natural disulfide bruguiesulfurol and biological evaluation of its derivatives as a novel scaffold for PTP1B inhibitors.
Bioorg Med Chem Lett
; 23(18): 5061-5, 2013 Sep 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-23942421