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1.
Biological and methodological complexities of beta-amyloid peptide: Implications for Alzheimer's disease research.
J Neurochem
; 160(4): 434-453, 2022 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-34767256
2.
Persistent DNA damage alters the neuronal transcriptome suggesting cell cycle dysregulation and altered mitochondrial function.
Eur J Neurosci
; 54(9): 6987-7005, 2021 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-34536321
3.
Transcriptomic Analysis of Human Astrocytes In Vitro Reveals Hypoxia-Induced Mitochondrial Dysfunction, Modulation of Metabolism, and Dysregulation of the Immune Response.
Int J Mol Sci
; 21(21)2020 Oct 28.
Artículo
en Inglés
| MEDLINE | ID: mdl-33126586
4.
NDRG2 Expression Correlates with Neurofibrillary Tangles and Microglial Pathology in the Ageing Brain.
Int J Mol Sci
; 21(1)2020 Jan 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-31947996
5.
Metallothionein-I/II expression associates with the astrocyte DNA damage response and not Alzheimer-type pathology in the aging brain.
Glia
; 66(11): 2316-2323, 2018 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-30098078
6.
Proteomic and cellular localisation studies suggest non-tight junction cytoplasmic and nuclear roles for occludin in astrocytes.
Eur J Neurosci
; 47(12): 1444-1456, 2018 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-29738614
7.
Neuronal DNA damage response-associated dysregulation of signalling pathways and cholesterol metabolism at the earliest stages of Alzheimer-type pathology.
Neuropathol Appl Neurobiol
; 42(2): 167-79, 2016 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-26095650
8.
A neuronal DNA damage response is detected at the earliest stages of Alzheimer's neuropathology and correlates with cognitive impairment in the Medical Research Council's Cognitive Function and Ageing Study ageing brain cohort.
Neuropathol Appl Neurobiol
; 41(4): 483-96, 2015 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-25443110
9.
Astrocytes and neuroinflammation in Alzheimer's disease.
Biochem Soc Trans
; 42(5): 1321-5, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25233410
10.
DNA damage response and senescence in endothelial cells of human cerebral cortex and relation to Alzheimer's neuropathology progression: a population-based study in the Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS) cohort.
Neuropathol Appl Neurobiol
; 40(7): 802-14, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24861546
11.
The United Kingdom Research study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH): protocol for a prospective longitudinal cohort study of healthcare and ancillary workers in UK healthcare settings.
BMJ Open
; 11(9): e050647, 2021 09 17.
Artículo
en Inglés
| MEDLINE | ID: mdl-34535484
12.
Amyloid binding and beyond: a new approach for Alzheimer's disease drug discovery targeting Aßo-PrPC binding and downstream pathways.
Chem Sci
; 12(10): 3768-3785, 2021 Feb 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-34163650
13.
Minocycline reduces the development of abnormal tau species in models of Alzheimer's disease.
FASEB J
; 23(3): 739-50, 2009 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-19001528
14.
Advanced Glycation End Product Formation in Human Cerebral Cortex Increases With Alzheimer-Type Neuropathologic Changes but Is Not Independently Associated With Dementia in a Population-Derived Aging Brain Cohort.
J Neuropathol Exp Neurol
; 79(9): 950-958, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32766675
15.
Glucosylpolyphenols as Inhibitors of Aß-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease.
J Med Chem
; 63(20): 11663-11690, 2020 10 22.
Artículo
en Inglés
| MEDLINE | ID: mdl-32959649
16.
Loss of IGF1R in Human Astrocytes Alters Complex I Activity and Support for Neurons.
Neuroscience
; 390: 46-59, 2018 10 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-30056117
17.
Cohort Profile: The United Kingdom Research study into Ethnicity and COVID-19 outcomes in Healthcare workers (UK-REACH).
Int J Epidemiol
; 52(1): e38-e45, 2023 02 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-36029521
18.
Kinase activities increase during the development of tauopathy in htau mice.
J Neurochem
; 103(6): 2256-67, 2007 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-17908241
19.
A reduced astrocyte response to ß-amyloid plaques in the ageing brain associates with cognitive impairment.
PLoS One
; 10(2): e0118463, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25707004
20.
The nuclear retention of transcription factor FOXO3a correlates with a DNA damage response and increased glutamine synthetase expression by astrocytes suggesting a neuroprotective role in the ageing brain.
Neurosci Lett
; 609: 11-7, 2015 Nov 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-26455863